Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 19/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 19/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 12/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 12/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14920560 | 0.85 | CHRM5 (0.49) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL534910 | 0.81 | CHRM5 (0.50) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL4049327 | 0.81 | SLC6A3 (0.60) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL17474611 | 0.81 | CHRM5 (0.68) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL20476229 | 0.80 | ALDH1A1 (0.50) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL23039761 | 0.79 | ALDH1A1 (0.46) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL18587017 | 0.78 | SMN1; SMN2 (0.44) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL23040394 | 0.77 | ALDH1A1 (0.47) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL21341963 | 0.77 | ADORA1 (0.48) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL20475211 | 0.76 | CHRM5 (0.48) | CHRM5CHRM1CHRM2CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773637-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | Xenon Pharmaceuticals Inc. (CA) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064983-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2013-05-10 | — | — | WO | disclosed |