Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CFTR | P13569 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196555 | 0.94 | LMNA (0.61) | LMNATSHRKMT2AALDH1A1MAPT | |
| SCHEMBL30488606 | 0.94 | LMNA (0.61) | LMNATSHRKMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL30910342 | 0.92 | LMNA (0.59) | LMNATSHRKMT2AALDH1A1MAPT | |
| SCHEMBL28324413 | 0.92 | LMNA (0.59) | LMNATSHRKMT2AALDH1A1MAPT | |
| SCHEMBL27542799 | 0.87 | CA1 (0.54) | LMNATSHRKMT2AALDH1A1MAPT | |
| Cadaverine Tartrate SCHEMBL29131137 | 0.82 | LMNA (0.52) | LMNATSHRKMT2AALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL30676257 | 0.82 | ALDH1A1 (0.49) | LMNATSHRKMT2AALDH1A1MAPT | |
| SCHEMBL31591207 | 0.79 | SLC6A3 (0.65) | LMNATSHRKMT2AALDH1A1MAPT | |
| SCHEMBL28982652 | 0.79 | LMNA (0.48) | LMNATSHRKMT2AALDH1A1MAPT | |
| Dimethyl Phthalate SCHEMBL790124 | 0.79 | TSHR (0.74) | LMNATSHRKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2020404-A1 | Cyanomethyl substituted N-Acyl Tryptamines | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-02-04 | — | — | EP | disclosed |