SCHEMBL196555

SCHEMBL196555

COC(=O)c1ccccc1Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.61
TSHR P16473 2/20 0.61
ALDH1A1 P00352 3/20 0.59
CFTR P13569 1/20 0.59
HSD17B10 Q99714 1/20 0.59
KMT2A Q03164 5/20 0.58
MAPT P10636 3/20 0.58
CES2 O00748 1/20 0.58
CES1 P23141 1/20 0.58
SLC6A4 P31645 1/20 0.58
SLC6A3 Q01959 1/20 0.58
POLB P06746 2/20 0.57
KDM4E B2RXH2 1/20 0.57
ATM Q13315 1/20 0.57
SMN1; SMN2 Q16637 2/20 0.54
MEN1 O00255 1/20 0.54
NR4A2 P43354 2/20 0.53
HPGD P15428 2/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30488606 1.00 LMNA (0.61) LMNATSHRALDH1A1CFTRHSD17B10
Hydrochloric Acid SCHEMBL30910342 0.98 LMNA (0.59) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL28324413 0.98 LMNA (0.59) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL4049407 0.94 LMNA (0.55) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL27542799 0.92 CA1 (0.54) LMNATSHRALDH1A1CFTRHSD17B10
Cadaverine Tartrate SCHEMBL29131137 0.88 LMNA (0.52) LMNATSHRALDH1A1CFTRHSD17B10
Trifluoroacetic Acid SCHEMBL30676257 0.88 ALDH1A1 (0.49) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL31591207 0.84 SLC6A3 (0.65) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL28982652 0.84 LMNA (0.48) LMNATSHRALDH1A1CFTRHSD17B10
Dimethyl Phthalate SCHEMBL790124 0.84 TSHR (0.74) LMNATSHRALDH1A1CFTRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 594 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823958-A Ketone reductase mutant and application thereof in synthesis of (R) -methyl o-chloromandelate 河北工业大学 2025-04-15 CN claimed
CN-119504512-A Method for preparing o-sulfonyl chloride/methyl aminobenzoate from o-chlorobenzoate 天津北方食品有限公司 2025-02-25 CN claimed
CN-119371582-A Polybutadiene composite rubber and preparation method thereof, rubber composition and application thereof 中国石油化工股份有限公司 2025-01-28 CN claimed
CN-119118829-A Method for preparing o-chlorobenzoic acid methyl ester by using o-chlorotoluene 天津北方食品有限公司 2024-12-13 CN claimed
WO-2024182515-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2024-09-06 WO claimed
US-20240292836-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2024-09-05 US claimed
CN-118308316-A Biocatalysis asymmetric reaction reductase and application thereof 湖州师范学院 2024-07-09 CN claimed
CN-118084672-A Method for preparing 5-chloro-2-nitrobenzoic acid methyl ester by adopting microchannel reactor 常州大学 2024-05-28 CN claimed
CN-116874364-A Preparation method of 5-bromo-2-chlorobenzoic acid 四平欧凯科技有限公司 2023-10-13 CN claimed
CN-107417669-B 3- (1H-indazole) -tetrahydropyrimidine-2-ketone compound, preparation method and application thereof 中国医学科学院药物研究所 2021-07-06 CN claimed
EP-2383275-A1 METHOD FOR SYNTHESIZING O-DIPHENYLPHOSPHINO BENZOIC ACID Sinomax Chemical Technology Co., Ltd (CN) 2011-11-02 EP claimed
WO-2011084691-A2 NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS BASF CORPORATION (US) 2011-07-14 WO claimed
US-20110152481-A1 Internal and external donor compounds for olefin polymerization catalysts BASF CATALYSTS LLC (US) 2011-06-23 US claimed
US-20110077426-A1 METHOD FOR SYNTHESIS OF O-DIPHENYLPHOSPHINOBENZOIC ACID SINOMAX CHEMICAL TECHNOLOGY CO. LTD. (CN) 2011-03-31 US claimed
EP-1080072-B1 2-(2-CHLOROPHENYL)-3,4-DIHYDRO-2H-PYRROL DERIVATIVES BAYER CROPSCIENCE AG (DE) 2004-08-04 EP claimed
US-6489490-B1 PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2002-12-03 US claimed
WO-1998034995-A1 COMPOUNDS AND METHODS FOR DOPING LIQUID CRYSTAL HOSTS QUEEN'S UNIVERSITY AT KINGSTON (CA) 1998-08-13 WO claimed
US-5380910-A Dehalogeno coupling IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1995-01-10 US claimed
US-5159082-A Catalytic coupling of an aromatic sulfinic acid with an aromatic halogen compound MITSUBISHI KASEI CORPORATION (JP) 1992-10-27 US claimed
EP-0405389-A1 Process for producing an aromatic compound Mitsubishi Chemical Corporation (JP) 1991-01-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240292836-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF L3MBTL4, L3MBTL3, L3MBTL1 LMNA 2740/4885TSHR 3541/4885ALDH1A1 3333/4885
US-20110077426-A1 METHOD FOR SYNTHESIS OF O-DIPHENYLPHOSPHINOBENZOIC ACID PLCB1, DCPS, POF1B LMNA 3545/4885TSHR 4780/4885ALDH1A1 2332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.