Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12899381 | 0.85 | KMT2A (0.41) | ALDH1A1RAB9AKDM4ERECQL | |
| SCHEMBL13690889 | 0.85 | KMT2A (0.41) | ALDH1A1RAB9AKDM4ERECQL | |
| SCHEMBL1218374 | 0.81 | EPHX2 (0.33) | KDM4EL3MBTL1CNR2EPHX2 | |
| SCHEMBL13688986 | 0.80 | ALDH1A1 (0.42) | ALDH1A1RAB9AKDM4ERECQLHPGD | |
| SCHEMBL12898783 | 0.80 | ALDH1A1 (0.42) | ALDH1A1RAB9AKDM4ERECQLHPGD | |
| Hydrochloric Acid SCHEMBL1215813 | 0.79 | ALDH1A1 (0.41) | ALDH1A1RAB9AKDM4ERECQLHPGD | |
| SCHEMBL1217295 | 0.77 | ALDH1A1 (0.38) | ALDH1A1RAB9AKDM4ERECQLHPGD | |
| SCHEMBL1217313 | 0.73 | USP30 (0.44) | ALDH1A1CNR2 | |
| SCHEMBL2780999 | 0.72 | CNR2 (0.34) | CNR2 | |
| SCHEMBL2831684 | 0.70 | CTSK (0.34) | ALDH1A1KDM4ECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |