Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8827763 | 0.86 | P4HTM (0.53) | TDP1SRD5A2CASP6ALDH1A1LMNA | |
| SCHEMBL19745758 | 0.82 | MAPT (0.44) | TDP1POLBMAPK1MEN1KMT2A | |
| SCHEMBL5610043 | 0.76 | MAPT (0.42) | ERN1POLBKDM4EALDH1A1LMNA | |
| SCHEMBL28708413 | 0.76 | TDP1 (0.61) | TDP1ERN1SRD5A2BCL2L1BAD | |
| SCHEMBL6257899 | 0.75 | KDM4E (0.63) | MKNK1MKNK2ERN1POLBMEN1 | |
| SCHEMBL30213522 | 0.74 | P4HA1 (0.69) | MKNK1MKNK2MAP4K4BCL2L1BAD | |
| SCHEMBL31084434 | 0.74 | P4HA1 (0.69) | MKNK1MKNK2MAP4K4BCL2L1BAD | |
| SCHEMBL628405 | 0.74 | TDP1 (0.88) | TDP1SRD5A2POLBMAPK1CA12 | |
| SCHEMBL20704770 | 0.74 | P4HA1 (0.69) | MKNK1MKNK2MAP4K4BCL2L1BAD | |
| SCHEMBL5740183 | 0.74 | ALDH1A1 (0.53) | TDP1POLBCA1CA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824825-A4 | SUBSTITUTED PYRIDOXINES AS ANTI-PLATELET AGENTS | MEDICURE INT INC (BB) | 2009-07-08 | — | — | EP | disclosed |
| US-20080306108-A1 | Substituted Pyridoxines As Anti-Platelet Agents | MEDICURE INTERNATIONAL INC. (BB) | 2008-12-11 | — | — | US | disclosed |
| US-20080306108-A1 | Substituted Pyridoxines As Anti-Platelet Agents | MEDICURE INTERNATIONAL INC. (BB) | 2008-12-11 | — | — | US | disclosed |
| US-20080306108-A1 | Substituted Pyridoxines As Anti-Platelet Agents | MEDICURE INTERNATIONAL INC. (BB) | 2008-12-11 | — | — | US | disclosed |
| EP-1824825-A1 | SUBSTITUTED PYRIDOXINES AS ANTI-PLATELET AGENTS | Medicure International Inc. (BB) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006045203-A1 | SUBSTITUTED PYRIDOXINES AS ANTI-PLATELET AGENTS | MEDICURE INTERNATIONAL INC. (CA) | 2006-05-04 | — | — | WO | disclosed |
| US-20060094749-A1 | Substituted pyridoxines as anti-platelet agents | MEDICURE INTERNATIONAL INC. | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306108-A1 | Substituted Pyridoxines As Anti-Platelet Agents | PNPO, GP6, PFKP | TDP1 969/4885MKNK1 3428/4885MKNK2 2851/4885 |
| US-20060094749-A1 | Substituted pyridoxines as anti-platelet agents | PNPO, GP6, PFKP | TDP1 969/4885MKNK1 3428/4885MKNK2 2851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.