Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.49 |
| ▸ | CTSS | P25774 | 4/20 | 0.41 |
| ▸ | CTSL | P07711 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046943 | 0.94 | CTSK (0.50) | CTSKCTSSCTSLALDH1A1KDM4E | |
| SCHEMBL4049188 | 0.92 | CTSK (0.40) | CTSKCTSSCTSLALDH1A1RAB9A | |
| SCHEMBL4043226 | 0.88 | CTSK (0.40) | CTSKCTSSCTSLALDH1A1TAS1R3 | |
| SCHEMBL4045333 | 0.88 | CTSK (0.53) | CTSKCTSSCTSLALDH1A1KDM4E | |
| SCHEMBL4043401 | 0.86 | CTSK (0.47) | CTSKCTSSCTSLALDH1A1TAS1R3 | |
| SCHEMBL4043597 | 0.86 | CTSK (0.41) | CTSKCTSSCTSL | |
| SCHEMBL4050010 | 0.86 | CTSK (0.44) | CTSKCTSSCTSLALDH1A1CTSB | |
| SCHEMBL4046025 | 0.85 | CTSK (0.49) | CTSKCTSSCTSLALDH1A1TAS1R3 | |
| SCHEMBL4041452 | 0.85 | CTSK (0.49) | CTSKCTSSCTSLALDH1A1KDM4E | |
| SCHEMBL4042251 | 0.85 | CTSK (0.50) | CTSKCTSSCTSLALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |