Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043597 | 0.94 | CTSK (0.41) | CTSKPREPFAPSMN1; SMN2CTSL | |
| SCHEMBL4050228 | 0.92 | CTSK (0.49) | CTSKALDH1A1RAB9ANR2F2MAPT | |
| SCHEMBL4043678 | 0.89 | ALDH1A1 (0.38) | CTSKALDH1A1RAB9ANR2F2PREP | |
| SCHEMBL4045843 | 0.88 | CTSK (0.43) | CTSKPREPFAPCTSLCTSS | |
| SCHEMBL4044655 | 0.87 | CTSK (0.39) | CTSKRAB9APREPFAPLMNA | |
| SCHEMBL4046943 | 0.86 | CTSK (0.50) | CTSKALDH1A1KDM4ESMN1; SMN2CTSL | |
| SCHEMBL4046799 | 0.86 | ALDH1A1 (0.39) | CTSKALDH1A1PREPFAPCTSL | |
| SCHEMBL4044582 | 0.86 | CTSK (0.40) | CTSKPREPFAPKDM4ECTSL | |
| SCHEMBL4043756 | 0.86 | CTSK (0.40) | CTSKPREPFAPCTSLCTSS | |
| SCHEMBL4040451 | 0.85 | CTSK (0.41) | CTSKPREPFAPCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |