Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076314 | 0.84 | PNMT (0.44) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL7134588 | 0.84 | TSHR (0.54) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL4735612 | 0.84 | ALDH1A1 (0.54) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL2242560 | 0.84 | BCAT2 (0.55) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL731621 | 0.83 | HMGB1 (0.55) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL162322 | 0.82 | MAPT (0.52) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL5252886 | 0.82 | KDM4E (0.52) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL619877 | 0.82 | ALDH1A1 (0.52) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL6555382 | 0.82 | MAPT (0.52) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL136079 | 0.82 | FOLH1 (0.59) | KDM4EALDH1A1MAPTTSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101795688-B | Application of 4- (pyrrolidine-1-yl) quinoline compound in preparation of medicine for killing clinically latent microorganisms | HELPERBY THERAPEUTICS LTD | 2015-05-20 | — | — | CN | claimed |
| JP-4791460-B2 | — | — | 2011-10-12 | — | — | JP | claimed |
| CN-100354252-C | Production process of aminomethyl group-containing benzamide compound | SHOWA DENKO KK (JP) | 2007-12-12 | — | — | CN | claimed |
| EP-1773786-A2 | FIVE-MEMBERED HETEROCYCLES USEFUL AS SERINE PROTEASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2007-04-18 | — | — | EP | claimed |
| WO-2005123050-A2 | FIVE-MEMBERED HETEROCYCLES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-12-29 | — | — | WO | claimed |
| CN-1656056-A | Production process of aminomethyl group-containing benzamide compound | SHOWA DENKO KK (JP) | 2005-08-17 | — | — | CN | claimed |
| EP-1506160-A1 | PRODUCTION PROCESS OF AMINOMETHYL GROUP-CONTAINING BENZAMIDE COMPOUND | Showa Denko K.K. (JP) | 2005-02-16 | — | — | EP | claimed |
| WO-2003097579-A1 | PRODUCTION PROCESS OF AMINOMETHYL GROUP-CONTAINING BENZAMIDE COMPOUND | SHOWA DENKO K. K. (JP) | 2003-11-27 | — | — | WO | claimed |
| US-4016257-A | Amide derivatives of acids, an antibiotic produced by Polyangium cellulosum var. fulvum | WARNER-LAMBERT COMPANY (US) | 1977-04-05 | — | — | US | claimed |
| CN-116444381-B | Xylylenediamine and a ring preparation method of hexamethylenediamine | 江西仰立新材料有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-117940388-A | Method for producing mineral fibre products | 洛科威有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117839717-A | Catalyst and method for coproducing XDA and BAC through XPN hydrogenation | 万华化学集团股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117279872-A | Method for producing mineral wool products | 洛科威有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-117164251-A | Mineral wool binder | 洛科威有限公司 | 2023-12-05 | — | — | CN | disclosed |
| EP-0817630-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996037204-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-11-28 | — | — | WO | disclosed |
| US-5578629-A | ANTICARCINOGENIC AGENTS | MERCK & CO., INC. (US) | 1996-11-26 | — | — | US | disclosed |
| WO-1996030015-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | disclosed |
| US-5534537-A | Prodrugs of inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1996-07-09 | — | — | US | disclosed |
| US-4016257-A | Amide derivatives of acids, an antibiotic produced by Polyangium cellulosum var. fulvum | WARNER-LAMBERT COMPANY (US) | 1977-04-05 | — | — | US | disclosed |