Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | FABP4 | P15090 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR1F | P30939 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698367 | 0.83 | HTR6 (0.56) | HTR6CYP3A4FABP4CA1CA2 | |
| SCHEMBL5746143 | 0.79 | HTR6 (0.68) | HTR6CYP3A4CYP2D6HTR1AHTR1D | |
| SCHEMBL29686864 | 0.79 | HTR6 (0.68) | HTR6CYP3A4CYP2D6HTR1AHTR1D | |
| SCHEMBL3427594 | 0.77 | HTT (0.62) | HTR6CYP3A4CYP2D6FABP4CA1 | |
| SCHEMBL3625322 | 0.77 | FABP4 (0.59) | HTR6CYP3A4CYP2D6FABP4 | |
| SCHEMBL1537823 | 0.75 | HTR6 (0.76) | HTR6CYP3A4CYP2D6HTR1A | |
| SCHEMBL4562485 | 0.74 | HTR6 (0.59) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL260867 | 0.73 | HTR6 (0.68) | HTR6CYP3A4CYP2D6HTR1AHTR1D | |
| SCHEMBL30644286 | 0.73 | HTR6 (0.68) | HTR6CYP3A4CYP2D6HTR1AHTR1D | |
| SCHEMBL11218072 | 0.72 | HTR6 (0.59) | HTR6HTR1AHTR1DHTR1BHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034581-A1 | SUBSTITUTED INDOLYL COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2009-03-19 | — | — | WO | disclosed |