Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246716 | 0.80 | PSIP1 (0.56) | PSIP1HTR6HSD11B1ALDH1A1HSD17B10 | |
| SCHEMBL64761 | 0.78 | PSIP1 (0.67) | PSIP1HTR6HSD11B1ALDH1A1HSD17B10 | |
| SCHEMBL777601 | 0.78 | PSIP1 (0.67) | PSIP1HTR6HSD11B1ALDH1A1HSD17B10 | |
| SCHEMBL2454944 | 0.77 | PSIP1 (0.58) | PSIP1HTR6HSD11B1ALDH1A1HSD17B10 | |
| SCHEMBL245358 | 0.77 | PSIP1 (0.52) | PSIP1HTR6HSD11B1ALDH1A1CA2 | |
| SCHEMBL3329009 | 0.76 | PSIP1 (0.64) | PSIP1HTR6HSD11B1ALDH1A1HSD17B10 | |
| SCHEMBL180713 | 0.76 | PSIP1 (1.00) | PSIP1HTR6HSD11B1ALDH1A1HSD17B10 | |
| SCHEMBL7865 | 0.75 | ALDH1A1 (0.61) | ALDH1A1CA12CA1CA2CA3 | |
| SCHEMBL2375552 | 0.75 | KMT2A (0.43) | PSIP1ALDH1A1TDP1SMN1; SMN2POLB | |
| SCHEMBL1540593 | 0.75 | PSIP1 (0.56) | PSIP1HTR6HSD11B1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4201 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024110477-A2 | SYNTHESIS OF A CYCLIC PEPTIDE | JANSSEN PHARMACEUTICA NV (BE) | 2024-05-30 | — | — | WO | claimed |
| WO-2024042448-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF RUXOLITINIB | GRANULES INDIA LIMITED (IN) | 2024-02-29 | — | — | WO | claimed |
| CN-110678447-B | Modified nucleic acid monomer compounds and oligonucleotide analogues | 卫材R&D管理有限公司 | 2023-12-12 | — | — | CN | claimed |
| EP-3643706-B1 | MODIFIED NUCLEIC ACID MONOMERS AND OLIGONUCLEIC ACID ANALOGUES, WITH HIGH BIOLOGICAL STABILITY AND TARGET GENE SILENCING ACTIVITY, FOR USE IN THERAPY AND DIAGNOSIS OF CANCER AND VIRAL DISEASES | EISAI R&D MAN CO LTD (JP) | 2023-11-15 | — | — | EP | claimed |
| US-20230018780-A1 | METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND | NIPPON SHINYAKU CO., LTD. (JP) | 2023-01-19 | — | — | US | claimed |
| US-20230014840-A1 | METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND | NIPPON SHINYAKU CO., LTD. (JP) | 2023-01-19 | — | — | US | claimed |
| CN-114981280-A | Method for producing oligonucleotide compound | 日本新药株式会社 | 2022-08-30 | — | — | CN | claimed |
| CN-114981281-A | Method for producing oligonucleotide compound | 日本新药株式会社 | 2022-08-30 | — | — | CN | claimed |
| EP-3985008-A1 | PROCESSES AND INTERMEDIATES FOR MAKING A JAK INHIBITOR | Incyte Holdings Corporation (US) | 2022-04-20 | — | — | EP | claimed |
| CN-111875607-B | Preparation method of chiral pyrrolopyrimidine compound | 正大天晴药业集团股份有限公司 | 2021-12-03 | — | — | CN | claimed |
| WO-1997013772-A2 | CEPHALOSPORIN ANTIBIOTICS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-04-17 | — | — | WO | claimed |
| EP-0635500-A1 | 5,6-Dihydro-(4H)1,3-oxazine and -thiazine derivatives as insecticides | YASHIMA CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-01-25 | — | — | EP | claimed |
| WO-1993001810-A1 | ANALOGS OF CALICHEAMICIN η1I, METHOD OF MAKING AND USING THE SAME | THE SCRIPPS RESEARCH INSTITUTE (US) | 1993-02-04 | — | — | WO | claimed |
| EP-0194984-B1 | DERIVATIVES OF IMIDAZOLE, THEIR PREPARATION AND UTILISATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES | CONTINENTAL PHARMA, INC. (BE) | 1990-04-04 | — | — | EP | claimed |
| EP-0304910-A1 | Biarylalkylimidazole derivatives as antidepressants | G.D. Searle & Co. (US) | 1989-03-01 | — | — | EP | claimed |
| US-4734410-A | Lactam derivatives and their use as hypotensive agents | SANKYO COMPANY LIMITED (JP) | 1988-03-29 | — | — | US | claimed |
| EP-0194984-A1 | Derivatives of imidazole, their preparation and utilisation, and pharmaceutical compositions containing these derivatives | CONTINENTAL PHARMA, INC. (BE) | 1986-09-17 | — | — | EP | claimed |
| EP-0006693-A1 | N-substituted trialkylstannylhydrocarbylcarboxylic acid hydrazides, methods of their preparation and insecticide compositions containing them | UNIROYAL, INC. (US) | 1980-01-09 | — | — | EP | claimed |
| US-4178382-A | INSECTICIDE FOR COTTON | UNIROYAL, INC. (US) | 1979-12-11 | — | — | US | claimed |
| US-3985726-A | DYEING AND PRINTING LEATHER, WOOL, SILK AND SYNTHETIC FIBERS | CIBA-GEIGY AG (CH) | 1976-10-12 | — | — | US | claimed |