Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.64 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14401296 | 0.81 | PSIP1 (0.61) | PSIP1HTR6HSD11B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL64761 | 0.80 | PSIP1 (0.67) | PSIP1HTR6HSD11B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL777601 | 0.80 | PSIP1 (0.67) | PSIP1HTR6HSD11B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2454944 | 0.79 | PSIP1 (0.58) | PSIP1HTR6HSD11B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL180713 | 0.78 | PSIP1 (1.00) | PSIP1HTR6HSD11B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6757831 | 0.77 | PSIP1 (0.56) | PSIP1HTR6HSD11B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1856258 | 0.76 | PSIP1 (0.61) | PSIP1HTR6HSD11B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11803160 | 0.76 | PSIP1 (0.61) | PSIP1HTR6HSD11B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9043800 | 0.76 | PSIP1 (0.61) | PSIP1HTR6HSD11B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8395368 | 0.76 | PSIP1 (0.61) | PSIP1HTR6HSD11B1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490367-B1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LTD (GB) | 2008-07-23 | — | — | EP | claimed |
| US-7348339-B2 | 2-(4-amino-furazan-3-yl)-1-ethyl-N-[(2R)-2-morpholinylmethyl]-1H-imidazo[4,5-c]pyridine-7-carboxamide; Mitogen- and Stress-Activated Protein (MSK) and Rho (guanosine triphosphate) 1 or 2 kinase inhibitor; neurodegenerative diaeases; antiinflammatory, anticarcinogenic, antiviral and antibacterial agent | GLAXO GROUP LIMITED (GB) | 2008-03-25 | — | — | US | claimed |
| US-20050197328-A1 | Imidazopyridine derivatives as kinase inhibitors | GLAXO GROUP LIMITED (GB) | 2005-09-08 | — | — | US | claimed |
| EP-1490367-A1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-29 | — | — | EP | claimed |
| WO-2003080610-A1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-10-02 | — | — | WO | claimed |
| US-4841030-A | Azo reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | claimed |
| EP-2177519-B1 | TETRAZOYLOXIME DERIVATIVE AND PLANT DISEASE CONTROL AGENT | NIPPON SODA CO (JP) | 2015-05-27 | — | — | EP | disclosed |
| US-9029552-B2 | Tetrazoyloxime derivative and plant disease control agent | NIPPON SODA CO., LTD. (JP) | 2015-05-12 | — | — | US | disclosed |
| US-20140005385-A1 | TETRAZOYLOXIME DERIVATIVE AND PLANT DISEASE CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2014-01-02 | — | — | US | disclosed |
| EP-2669282-A1 | Tetrazoyloxime derivative and plant disease control agent | NIPPON SODA CO., LTD. (JP) | 2013-12-04 | — | — | EP | disclosed |
| US-20100137594-A1 | TETRAZOYLOXIME DERIVATIVE AND PLANT DISEASE CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| EP-2177519-A1 | TETRAZOYLOXIME DERIVATIVE AND PLANT DISEASE CONTROL AGENT | Nippon Soda Co., Ltd. (JP) | 2010-04-21 | — | — | EP | disclosed |
| EP-1490367-B1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LTD (GB) | 2008-07-23 | — | — | EP | disclosed |
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197328-A1 | Imidazopyridine derivatives as kinase inhibitors | NR4A3, XDH, MAPK8 | PSIP1 2534/4885HTR6 2281/4885HSD11B1 1752/4885 |
| US-20140005385-A1 | TETRAZOYLOXIME DERIVATIVE AND PLANT DISEASE CONTROL AGENT | PAOX, BROX, TTI2 | PSIP1 2518/4885HTR6 4728/4885HSD11B1 2789/4885 |
| US-20100137594-A1 | TETRAZOYLOXIME DERIVATIVE AND PLANT DISEASE CONTROL AGENT | PAOX, H1-10, HAX1 | PSIP1 4363/4885HTR6 3671/4885HSD11B1 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.