Desflurane

Desflurane

SCHEMBL4052017

FC(F)O[C@H](F)C(F)(F)F

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGLRA1GLRBKCNK10KCNK18KCNK2KCNK3KCNK9

The experimentally established mechanism targets of Desflurane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Desflurane SCHEMBL62917 1.00 MEN1 (0.50) MEN1KMT2A
Desflurane SCHEMBL14895053 0.88 MEN1 (0.42) MEN1KMT2A
SCHEMBL710347 0.85 MEN1 (0.40) MEN1KMT2A
Desflurane SCHEMBL23212096 0.82 MEN1 (0.37) MEN1KMT2A
Desflurane SCHEMBL3859599 0.80 MEN1 (0.36) MEN1KMT2A
SCHEMBL29655881 0.80 MEN1 (0.40) MEN1KMT2A
SCHEMBL28879022 0.79 MEN1 (0.36) MEN1KMT2A
SCHEMBL30956645 0.76 MEN1 (0.35) MEN1KMT2A
SCHEMBL29655935 0.74 MEN1 (0.35) MEN1KMT2A
SCHEMBL3267457 0.73 MEN1 (0.39) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020079299-A1 MICROSPHERES FOR THE TREATMENT OF MUSCULOSKELETAL AND VASCULAR SKIN OR DERMATOLOGICAL DISORDERS PIDAGEMA, S.L (ES) 2020-04-23 WO claimed
WO-2025068735-A1 DEVICE FOR ATTACHING AN ENDOTRACHEAL TUBE AND BREATHING CIRCUIT VELEZ ROJAS ARMANDO DE JESUS (MX) 2025-04-03 WO disclosed
WO-2020079299-A1 MICROSPHERES FOR THE TREATMENT OF MUSCULOSKELETAL AND VASCULAR SKIN OR DERMATOLOGICAL DISORDERS PIDAGEMA, S.L (ES) 2020-04-23 WO disclosed
WO-2014170858-A1 PROCESS FOR THE PURIFICATION OF ANESTHESIA GASES USING MEMBRANE CONTACTORS AND ITS APPLICATIONS GRAÇA NEVES LUÍSA ALEXANDRA (PT) 2014-10-23 WO disclosed
WO-2009120057-A1 CARTRIDGES OF LIQUID ANAESTHETIC AND VAPORISER INNOVAMÉDICA S.A.P.I. DE C.V. (MX) 2009-10-01 WO disclosed
WO-1999052580-A1 AUTOMATIC CONTROL METHOD FOR SUPPLYING ANAESTHETIC TO A LOW FLOW-TYPE CLOSED CIRCUIT MAS MARFANY JAIME (ES) 1999-10-21 WO disclosed