Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGLRA1GLRBKCNK10KCNK18KCNK2KCNK3KCNK9
The experimentally established mechanism targets of Desflurane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Desflurane SCHEMBL4052017 | 1.00 | MEN1 (0.50) | MEN1KMT2A | |
| Desflurane SCHEMBL14895053 | 0.88 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL710347 | 0.85 | MEN1 (0.40) | MEN1KMT2A | |
| Desflurane SCHEMBL23212096 | 0.82 | MEN1 (0.37) | MEN1KMT2A | |
| Desflurane SCHEMBL3859599 | 0.80 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL29655881 | 0.80 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL28879022 | 0.79 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL30956645 | 0.76 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL29655935 | 0.74 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL3267457 | 0.73 | MEN1 (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6861 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719552-A1 | INDUCTION OF GENERAL ANESTHESIA IN ADULTS UNDERGOING ELECTIVE SURGERY | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2026-04-08 | — | — | EP | claimed |
| US-12594388-B2 | Device to deliver a predetermined amount of a substance to a natural orifice of the body | APTARGROUP, INC. (US) | 2026-04-07 | — | — | US | claimed |
| EP-4157407-B1 | INHALER DEVICE FOR INHALABLE LIQUIDS | MEDICAL DEVELOPMENTS INTERNATIONAL LTD (AU) | 2026-03-25 | — | — | EP | claimed |
| US-20260076872-A1 | POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME | SIO2 MEDICAL PRODUCTS LLC (US) | 2026-03-19 | — | — | US | claimed |
| EP-4698258-A1 | LOW INTERNAL RESISTANCE POLYMER PARTITIONED ANESTHETIC VAPORIZER SYSTEM AND METHOD | Rheos Medical Corp. (US) | 2026-02-25 | — | — | EP | claimed |
| EP-4293681-B1 | SYSTEMS AND METHODS FOR MANAGING AIR QUALITY IN A SURGICAL ENVIRONMENT | STRYKER CORP (US) | 2025-12-10 | — | — | EP | claimed |
| EP-4651926-A1 | DEVICES, SYSTEMS, AND METHODS FOR ADMINISTERING HYDROGEN GAS | H2 Water Technologies Ltd (CA) | 2025-11-26 | — | — | EP | claimed |
| EP-3801712-B1 | SYSTEM FOR CONTROLLING GAS COMPOSITION IN A SURGICAL CAVITY DURING ENDOSCOPIC SURGICAL PROCEDURES | CONMED CORP (US) | 2025-11-05 | — | — | EP | claimed |
| EP-4629041-A2 | IMPROVEMENTS IN OR RELATING TO PATIENT CARE | Peninsula Medical Technologies Ltd (GB) | 2025-10-08 | — | — | EP | claimed |
| EP-4602126-A1 | INVERTED BAROCALORIC EFFECTS | President and Fellows of Harvard College (US) | 2025-08-20 | — | — | EP | claimed |
| WO-1993004138-A1 | CHLORINE-FREE FLUOROCARBON REFRIGERANT | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-04 | — | — | WO | claimed |
| EP-0341004-B1 | A METHOD OF PREPARING 2-(DIFLUOROMETHOXY)-1,1,1,2-TETRAFLUOROETHANE | Anaquest, Inc. (US) | 1992-11-25 | — | — | EP | claimed |
| US-5114715-A | METHODS OF USE AND COMPOSITIONS OF (S)-ISOFLURANE AND (S)-DESFLURANE | SEPRACOR INC. (US) | 1992-05-19 | — | — | US | claimed |
| US-5114714-A | METHODS OF USE AND COMPOSITIONS OF (R)-ISOFLURANE AND (R)-DESFLURANE | SEPRACOR, INC. (US) | 1992-05-19 | — | — | US | claimed |
| EP-0285237-B1 | 2-(DIFLUROMETHOXY)-1,1,1,2-TETRAFLUOROETHANE AS AN ANAESTHETIC | Ohmeda Pharmaceutical Products Division Inc. (US) | 1992-05-13 | — | — | EP | claimed |
| US-5015781-A | Forming 2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane from 2-(difluoromethoxy)-1,1,1-trifluoro-2-chloroethane by reaction with bromine trifluoride | BOC, INC. (US) | 1991-05-14 | — | — | US | claimed |
| EP-0341004-A2 | A method of preparing 2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane | Anaquest, Inc. (US) | 1989-11-08 | — | — | EP | claimed |
| US-4874901-A | USING SODIUM OR POTASSIUM FLUORIDE | BOC, INC. (US) | 1989-10-17 | — | — | US | claimed |
| EP-0285237-A2 | 2-(Difluromethoxy)-1,1,1,2-tetrafluoroethane as an anaesthetic | Ohmeda Pharmaceutical Products Division Inc. (US) | 1988-10-05 | — | — | EP | claimed |
| US-4762856-A | 2-(DIFLUOROMETHOXY)-1,1,1,2-TETRAFLUOROETHANE, INHALATION | BOC, INC. (US) | 1988-08-09 | — | — | US | claimed |