Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052922 | 1.00 | ALOX5 (0.52) | ALOX5PTPN1PPARGPPARDAR | |
| SCHEMBL4052876 | 0.92 | PTPN1 (0.49) | ALOX5PTPN1ARHPGDCISD1 | |
| SCHEMBL4052873 | 0.92 | PTPN1 (0.49) | ALOX5PTPN1ARHPGDCISD1 | |
| SCHEMBL4050517 | 0.91 | HPGD (0.48) | ALOX5PTPN1ARHPGD | |
| SCHEMBL4050515 | 0.91 | HPGD (0.48) | ALOX5PTPN1ARHPGD | |
| SCHEMBL4054941 | 0.91 | HPGD (0.48) | ALOX5PTPN1HPGDMEN1MITF | |
| SCHEMBL4054943 | 0.91 | HPGD (0.48) | ALOX5PTPN1HPGDMEN1MITF | |
| SCHEMBL4054032 | 0.91 | ALOX5 (0.46) | ALOX5PTPN1ARHPGDENPP2 | |
| SCHEMBL4054034 | 0.91 | ALOX5 (0.46) | ALOX5PTPN1ARHPGDENPP2 | |
| SCHEMBL4059813 | 0.91 | ALOX5 (0.41) | ALOX5PTPN1ARHPGDCISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |