Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 6/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054032 | 1.00 | ALOX5 (0.46) | ALOX5HPGDPTPN1POLBMAOA | |
| SCHEMBL4052873 | 0.92 | PTPN1 (0.49) | ALOX5HPGDPTPN1POLBMAOA | |
| SCHEMBL4052876 | 0.92 | PTPN1 (0.49) | ALOX5HPGDPTPN1POLBMAOA | |
| SCHEMBL4052922 | 0.91 | ALOX5 (0.52) | ALOX5HPGDPTPN1ARENPP2 | |
| SCHEMBL4054941 | 0.91 | HPGD (0.48) | ALOX5HPGDPTPN1RAB9A | |
| SCHEMBL4052918 | 0.91 | ALOX5 (0.52) | ALOX5HPGDPTPN1ARENPP2 | |
| SCHEMBL4054943 | 0.91 | HPGD (0.48) | ALOX5HPGDPTPN1RAB9A | |
| SCHEMBL4050517 | 0.91 | HPGD (0.48) | ALOX5HPGDPTPN1POLBMAOA | |
| SCHEMBL4050515 | 0.91 | HPGD (0.48) | ALOX5HPGDPTPN1POLBMAOA | |
| SCHEMBL4058075 | 0.90 | PTPN1 (0.45) | ALOX5HPGDPTPN1POLBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |