Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | FABP4 | P15090 | 5/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.42 |
| ▸ | UTRN | P46939 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051457 | 0.90 | VSIR (0.56) | FFAR1PPARDPPARAFABP4VSIR | |
| SCHEMBL4058058 | 0.89 | CEPT1 (0.50) | VSIRCETPCEPT1GPR119UTRN | |
| SCHEMBL13608541 | 0.87 | GPR119 (0.49) | FFAR1PPARDPPARAVSIRCETP | |
| SCHEMBL4051596 | 0.85 | GPR119 (0.55) | FFAR1PPARDPPARAVSIRGPR119 | |
| SCHEMBL4055472 | 0.83 | GPR119 (0.52) | VSIRGPR119UTRN | |
| SCHEMBL4050525 | 0.82 | GPR119 (0.51) | VSIRGPR119HPSEUTRNKDM4E | |
| SCHEMBL4054837 | 0.82 | UTRN (0.46) | VSIRGPR119UTRNKDM4EMEN1 | |
| SCHEMBL4231839 | 0.82 | GPR119 (0.46) | VSIRGPR119UTRNKDM4EMEN1 | |
| SCHEMBL4051369 | 0.80 | PPARD (0.47) | FFAR1PPARDPPARAFABP4VSIR | |
| SCHEMBL4055618 | 0.79 | FFAR1 (0.50) | FFAR1PPARDPPARAFABP4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622479-B2 | Bicyclic derivative, its production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |
| US-20050101647-A1 | Bicyclic derivative, its production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-05-12 | — | — | US | disclosed |
| EP-1460067-A1 | BICYCLIC DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Chemical Industries, Ltd. (JP) | 2004-09-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101647-A1 | Bicyclic derivative, its production and use | ABL1, SRC, PTK2B | FFAR1 3632/4885PPARD 4320/4885PPARA 3864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.