Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4154924 | 0.78 | LMNA (0.45) | MAPTSMN1; SMN2HTTTP53 | |
| SCHEMBL4048036 | 0.78 | MAPT (0.43) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL3949058 | 0.72 | ADRA2C (0.67) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL4049999 | 0.69 | L3MBTL1 (0.38) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL4158829 | 0.69 | SLC6A2 (0.40) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL3958750 | 0.69 | ALDH1A1 (0.68) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL13162094 | 0.65 | ALDH1A1 (0.50) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL11490697 | 0.65 | MAPT (0.43) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL3959407 | 0.65 | SLC6A2 (0.54) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL3959433 | 0.64 | ADRA2C (0.44) | KDM4EALDH1A1ADRA2CNPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009032754-A2 | HETEROCYCLODIAZEPINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-03-12 | — | — | WO | disclosed |