Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052664 | 0.87 | RAB9A (0.55) | RAB9AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL23223734 | 0.86 | RAB9A (0.69) | RAB9AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL11614936 | 0.86 | RAB9A (0.69) | RAB9AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL4048884 | 0.85 | RAB9A (0.50) | RAB9AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL4052107 | 0.84 | ALDH1A1 (0.56) | RAB9AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL44697 | 0.84 | TYR (0.52) | RAB9AALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL4052995 | 0.84 | RXRA (0.61) | RAB9AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL4048858 | 0.84 | RXRA (0.61) | RAB9AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL4052838 | 0.82 | HPGD (0.57) | RAB9AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL13462927 | 0.81 | SMN1; SMN2 (0.75) | RAB9AALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |