Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30623084 | 1.00 | CYP2A6 (0.41) | CYP2A6ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL28745027 | 0.94 | CYP2A6 (0.37) | CYP2A6ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL226062 | 0.81 | CYP2A6 (0.50) | CYP2A6ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL30714252 | 0.81 | CYP2A6 (0.50) | CYP2A6ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL28744566 | 0.76 | CYP2A6 (0.50) | CYP2A6ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL13742552 | 0.75 | DYRK1A (0.48) | CYP2A6SIGMAR1DYRK1AMRGPRX4 | |
| SCHEMBL164774 | 0.73 | CYP2A6 (0.50) | CYP2A6ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL18725843 | 0.71 | CYP2A6 (0.36) | CYP2A6SIGMAR1DYRK1AMRGPRX4 | |
| SCHEMBL911044 | 0.71 | ESR1 (0.44) | CYP2A6HTTCYP1A2MRGPRX4 | |
| SCHEMBL276241 | 0.71 | CYP2A6 (0.41) | CYP2A6SIGMAR1DYRK1AMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 545 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853795-A | Arylboron compound of conjugated olefin and preparation method and application thereof | 南京工业大学 | 2022-08-05 | — | — | CN | claimed |
| CN-113956268-B | 6-bromo-1-chlorobenzothiophene [2,3-c ] pyridine and synthetic method | 西安欧得光电材料有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-113956268-A | 6-bromo-1-chlorobenzothiophene [2,3-c ] pyridine and synthetic method | 西安欧得光电材料有限公司 | 2022-01-21 | — | — | CN | claimed |
| EP-4744661-A2 | NOVEL PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-05-20 | — | — | EP | disclosed |
| EP-4709481-A1 | 5,6-FUSED AND 6,6-FUSED BICYCLIC ALCOHOLS AND ETHERS AND COMPOSITIONS FOR USE AS 15-PROSTAGLANDIN DEHYDROGENASE MODULATORS | Amgen Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| US-12569466-B2 | Short-acting psychoactive compounds of the MDMA class | APOAPSIS HOLDINGS, LLC (US) | 2026-03-10 | — | — | US | disclosed |
| EP-4658656-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | Beone Medicines I GmbH (CH) | 2025-12-10 | — | — | EP | disclosed |
| EP-4298092-B1 | NOVEL PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2025-11-26 | — | — | EP | disclosed |
| US-20250346597-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | BEONE MEDICINES I GMBH (CH) | 2025-11-13 | — | — | US | disclosed |
| US-12459912-B2 | Advantageous benzothiophene compositions for mental disorders or enhancement | TACTOGEN INC (US) | 2025-11-04 | — | — | US | disclosed |
| US-20250289812-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | RUIJIN HOSPITAL, SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE (CN) | 2025-09-18 | — | — | US | disclosed |
| EP-1204660-A1 | SEROTONERGIC BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001068653-A1 | DIHYDROIMIDAZO[2,1-B]THIAZOLE AND DIHYDRO-5H-THIAZOLO[3,2-A]PYRIMIDINES AS ANTIDEPRESSANT AGENTS | KNOLL GMBH (DE) | 2001-09-20 | — | — | WO | disclosed |
| EP-1104754-A1 | NOVEL SULFONYL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |
| WO-2001009126-A1 | SEROTONERGIC BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |
| EP-0526951-A1 | 3-Phenyl benzo b thiophenes as pesticidal compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-02-10 | — | — | EP | disclosed |
| EP-0125059-B1 | HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES | ICI AUSTRALIA LIMITED (AU) | 1991-02-27 | — | — | EP | disclosed |
| US-4853380-A | REACTING SULFONATED HETEROCYCLIC SULFUR COMPOUNDS WITH DIAMINES OF PLATINUM NITRATE | INTERNATIONAL PHARMACEUTICAL PRODUCTS (US) | 1989-08-01 | — | — | US | disclosed |
| US-4664693-A | POSTEMERGENCE | ICI AUSTRALIA LIMITED (AU) | 1987-05-12 | — | — | US | disclosed |
| EP-0125059-A2 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1984-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250289812-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | ITGB3, SRC, FYN | CYP2A6 3393/4885ALDH1A1 4001/4885MAPT 2125/4885 |
| US-20250346597-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | DGKG, DGKA, DGKK | CYP2A6 4672/4885ALDH1A1 4075/4885MAPT 4168/4885 |
| US-12459912-B2 | Advantageous benzothiophene compositions for mental disorders or enhancement | SLC6A3, CREBBP, SLC1A2 | CYP2A6 1879/4885ALDH1A1 2491/4885MAPT 63/4885 |
| US-12569466-B2 | Short-acting psychoactive compounds of the MDMA class | HTR2C, SLC6A2, DRD2 | CYP2A6 284/4885ALDH1A1 1469/4885MAPT 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.