Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | VCP | P55072 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.45 |
| ▸ | TPH1 | P17752 | 2/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565563 | 0.88 | GRIN2B (0.62) | GRIN2BCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4562339 | 0.87 | GPR119 (0.49) | GRIN2BCYP3A4CYP2D6CYP2C9VCP | |
| SCHEMBL4049787 | 0.87 | TPH1 (0.49) | GRIN2BCYP3A4CYP2D6CYP2C9VCP | |
| SCHEMBL13690743 | 0.86 | VCP (0.48) | GRIN2BCYP3A4CYP2D6CYP2C9VCP | |
| SCHEMBL4055884 | 0.86 | GPR119 (0.59) | GRIN2BGPR119TPH1 | |
| SCHEMBL13690387 | 0.86 | GPR119 (0.59) | GPR119 | |
| SCHEMBL4051025 | 0.84 | GPR119 (0.47) | GRIN2BCYP3A4CYP2D6CYP2C9GPR119 | |
| SCHEMBL4566452 | 0.84 | GPR119 (0.61) | GRIN2BCYP3A4CYP2D6CYP2C9VCP | |
| SCHEMBL4056120 | 0.84 | GPR119 (0.51) | NPY2RGPR119GAA | |
| SCHEMBL13690456 | 0.83 | GPR119 (0.43) | GRIN2BCYP3A4CYP2D6CYP2C9VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |