Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2874877 | 0.74 | TSHR (0.43) | CYP2D6SLC6A3TSHRCYP1A2CYP3A4 | |
| SCHEMBL10347811 | 0.70 | SLC6A3 (0.50) | CYP2D6SLC6A3TSHRCYP1A2CYP3A4 | |
| SCHEMBL28664540 | 0.67 | SRC (0.47) | CYP2D6SRC | |
| SCHEMBL4055535 | 0.67 | ALDH1A1 (0.49) | CYP2D6SLC6A3CYP3A4KMT2ASRC | |
| SCHEMBL9861793 | 0.67 | SRC (0.42) | CYP2D6SLC6A3TSHRCYP1A2CYP3A4 | |
| SCHEMBL3955535 | 0.65 | CYP2D6 (0.42) | CYP2D6TSHRKMT2ASRCLMNA | |
| SCHEMBL3962465 | 0.65 | HPGD (0.39) | KMT2ALMNAMAPK1ALDH1A1CYP2A6 | |
| SCHEMBL858 | 0.65 | CYP2D6 (0.42) | CYP2D6SLC6A3TSHRCYP1A2SLC6A4 | |
| SCHEMBL10743810 | 0.65 | LMNA (0.42) | CYP2D6SLC6A3TSHRCYP1A2CYP3A4 | |
| SCHEMBL12860871 | 0.65 | SLC6A3 (0.41) | CYP2D6SLC6A3TSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553646-B2 | Microbial sulfoxidation and amidation of benzhdrylsulfanyl carboxylic acids and uses thereof | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2009-06-30 | — | — | US | claimed |
| WO-2007027328-A2 | MICROBIAL SULFOXIDATION AND AMIDATION OF BENZHDRYLSULFANYL CARBOXYLIC ACIDS AND USES THEREOF | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2007-03-08 | — | — | WO | claimed |
| US-20070026507-A1 | MICROBIAL SULFOXIDATION AND AMIDATION OF BENZHDRYLSULFANYL CARBOXYLIC ACIDS AND USES THEREOF | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2007-02-01 | — | — | US | claimed |
| US-7553646-B2 | Microbial sulfoxidation and amidation of benzhdrylsulfanyl carboxylic acids and uses thereof | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2009-06-30 | — | — | US | disclosed |
| US-7553646-B2 | Microbial sulfoxidation and amidation of benzhdrylsulfanyl carboxylic acids and uses thereof | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2009-06-30 | — | — | US | disclosed |
| US-7553646-B2 | Microbial sulfoxidation and amidation of benzhdrylsulfanyl carboxylic acids and uses thereof | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2009-06-30 | — | — | US | disclosed |
| WO-2007027328-A3 | MICROBIAL SULFOXIDATION AND AMIDATION OF BENZHDRYLSULFANYL CARBOXYLIC ACIDS AND USES THEREOF | UNIV IOWA RES FOUND (US) | 2007-05-10 | — | — | WO | disclosed |
| WO-2007027328-A2 | MICROBIAL SULFOXIDATION AND AMIDATION OF BENZHDRYLSULFANYL CARBOXYLIC ACIDS AND USES THEREOF | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007027328-A2 | MICROBIAL SULFOXIDATION AND AMIDATION OF BENZHDRYLSULFANYL CARBOXYLIC ACIDS AND USES THEREOF | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2007-03-08 | — | — | WO | disclosed |
| US-20070026507-A1 | MICROBIAL SULFOXIDATION AND AMIDATION OF BENZHDRYLSULFANYL CARBOXYLIC ACIDS AND USES THEREOF | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2007-02-01 | — | — | US | disclosed |
| US-20070026507-A1 | MICROBIAL SULFOXIDATION AND AMIDATION OF BENZHDRYLSULFANYL CARBOXYLIC ACIDS AND USES THEREOF | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2007-02-01 | — | — | US | disclosed |