Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10743810 | 0.89 | LMNA (0.42) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL9561869 | 0.87 | IDO1 (0.50) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL28768584 | 0.80 | SLC6A4 (0.39) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL10734256 | 0.76 | ALDH1A1 (0.46) | TSHRCYP1A2CYP2C9SLC6A4CYP2C19 | |
| SCHEMBL913100 | 0.74 | KMT2A (0.41) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL28511593 | 0.74 | DPP4 (0.36) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL8823993 | 0.74 | DPP4 (0.36) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL11132156 | 0.74 | DPP4 (0.48) | DPP4F2HTR2ATAAR1 | |
| SCHEMBL3718532 | 0.74 | LMNA (0.41) | TSHRCYP2D6L3MBTL1SRC | |
| SCHEMBL4054070 | 0.74 | CYP2D6 (0.38) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104530417-B | A kind of multiple functionalized H types polyethyleneglycol derivative and preparation method thereof | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-08 | — | — | CN | claimed |
| CN-104530415-B | A kind of different functionalization Y types polyethyleneglycol derivative, preparation method and its bio-related substance | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-01 | — | — | CN | claimed |
| CN-104530415-A | Hetero-functionalized Y-type polyethylene glycol derivative, preparation method and biologically related substance thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| CN-104530417-A | Multifunctional H-type polyethylene glycol derivative and preparation method thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| CN-104109235-A | Mono-functionalized polyethylene glycol with nitrogen atom branched center and its preparation method and biologically-relevant matter | XIAMEN SINOPEG BIOTECH CO LTD | 2014-10-22 | — | — | CN | claimed |
| CN-101550044-B | Application of polyoxometalate/silicon dioxide catalyst in controllable oxidization of sulfide | UNIV JILIN | 2012-11-14 | — | — | CN | claimed |
| CN-101550044-A | Application of polyoxometalate/silicon dioxide catalyst in controllable oxidization of sulfide | UNIV JILIN (CN) | 2009-10-07 | — | — | CN | claimed |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2022-05-10 | — | — | US | disclosed |
| CN-110256307-A | A method of synthesis sulfoxide compound | 南京雷正医药科技有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-108091826-A | Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same | 三菱化学株式会社 | 2018-05-29 | — | — | CN | disclosed |
| CN-108054283-A | A kind of insensitive molybdenum trioxide anode interface layer of film thickness and preparation method thereof and the application in organic solar batteries | 中国科学院化学研究所 | 2018-05-18 | — | — | CN | disclosed |
| CN-104725628-B | A kind of single functionalization branched polyethylene glycol, preparation method and its bio-related substance containing degradable group | 厦门赛诺邦格生物科技股份有限公司 | 2018-04-17 | — | — | CN | disclosed |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2017-11-02 | — | — | US | disclosed |
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |
| WO-2000078725-A1 | SYNTHESIS OF SUBSTITUTED AMIDINES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |
| EP-1018984-A1 | MEDICAL DEVICE FOR $i(IN VIVO) NITRIC OXIDE RELEASE | Cordis Corporation (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999000070-A1 | MEDICAL DEVICE FOR IN VIVO NITRIC OXIDE RELEASE | CORDIS CORPORATION (US) | 1999-01-07 | — | — | WO | disclosed |
| US-3971627-A | MODIFIED POLYESTER, POLYAMIDE, POLYCARBONATE, POLYOLEFIN OR RAYON TIRE CORD | HERCULES INCORPORATED (US) | 1976-07-27 | — | — | US | disclosed |
| US-3971743-A | CROSSLINKING POLYMERS | HERCULES INCORPORATED (US) | 1976-07-27 | — | — | US | disclosed |
| US-3941751-A | Epoxy-azido compounds | HERCULES INCORPORATED (US) | 1976-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | HDGF, F11, F12 | TSHR 1973/4885SLC6A3 4728/4885CYP2D6 3820/4885 |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | HDGF, F11, F12 | TSHR 1973/4885SLC6A3 4728/4885CYP2D6 3820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.