Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.73 |
| ▸ | NPC1 | O15118 | 8/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | MAOB | P27338 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | GAPDH | P04406 | 2/20 | 0.68 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.59 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15476915 | 0.85 | MAPT (1.00) | RAB9AKDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL7124667 | 0.84 | KDM4E (0.75) | RAB9AKDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL30356319 | 0.83 | RAB9A (1.00) | RAB9AKDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL177366 | 0.83 | RAB9A (1.00) | RAB9AKDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL5085018 | 0.82 | MIF (0.72) | RAB9AKDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL8814114 | 0.81 | MAPT (1.00) | RAB9AKDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL22132745 | 0.81 | GAPDH (1.00) | RAB9AKDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL28068462 | 0.81 | RAB9A (0.71) | RAB9AKDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL12813278 | 0.80 | ADORA3 (0.57) | RAB9AKDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL5008342 | 0.79 | NPC1 (0.68) | RAB9AKDM4ENPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118338-A2 | USE OF A POLYPHENOLIC TYPE COMPOUND FOR PREVENTING OR TREATING A POLYGLUTAMINE EXPANSION NEURODEGENERATIVE DISEASE | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2009-10-01 | — | — | WO | claimed |
| WO-2012135493-A1 | POLYMERS AND TASK FUNCTIONALIZED POLYMERS FOR ENHANCED CHANGE DETECTION | ENVIRONMENTAL TECHNOLOGY SOLUTIONS (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2009118338-A2 | USE OF A POLYPHENOLIC TYPE COMPOUND FOR PREVENTING OR TREATING A POLYGLUTAMINE EXPANSION NEURODEGENERATIVE DISEASE | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2009-10-01 | — | — | WO | disclosed |