SCHEMBL4055579

SCHEMBL4055579

CCCc1ccc(C#Cc2ccc(OC(C)=O)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.55
ACACB O00763 15/20 0.55
ALDH1A1 P00352 1/20 0.50
PLA2G1B P04054 1/20 0.48
KMT2A Q03164 1/20 0.48
ATG4B Q9Y4P1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3899589 0.90 THRB (0.66) THRBACACBALDH1A1PLA2G1BKMT2A
SCHEMBL11785681 0.88 THRB (0.64) THRBACACBALDH1A1PLA2G1BKMT2A
SCHEMBL8904775 0.84 THRB (0.56) THRBACACBPLA2G1BKMT2AATG4B
SCHEMBL16327448 0.84 LMNA (0.61) ACACBALDH1A1KMT2A
SCHEMBL13845304 0.84 THRB (0.55) THRBALDH1A1PLA2G1BKMT2AATG4B
SCHEMBL74647 0.83 THRB (0.82) THRBACACBALDH1A1PLA2G1BKMT2A
SCHEMBL4057303 0.82 ACACB (0.59) ACACBKMT2A
SCHEMBL4065386 0.81 ELANE (0.51) THRBACACBALDH1A1PLA2G1BKMT2A
SCHEMBL9081470 0.80 LMNA (0.61) THRBALDH1A1KMT2A
SCHEMBL8904371 0.80 THRB (0.65) THRBACACBPLA2G1BKMT2AATG4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM THRB 4106/4885ACACB 4685/4885ALDH1A1 1552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.