SCHEMBL4055683

SCHEMBL4055683

Cc1cc(Cc2ccc(O)cc2)c(O)c(Cc2cc(C)cc(Cc3cc(C)cc(Cc4ccc(O)cc4)c3O)c2O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.58
CYP2C9 P11712 2/20 0.52
CYP2C19 P33261 2/20 0.52
HIF1A Q16665 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
ESR1 P03372 2/20 0.50
ESR2 Q92731 2/20 0.50
HSPA5 P11021 1/20 0.48
IDH1 O75874 2/20 0.47
KEAP1 Q14145 1/20 0.47
HSD17B10 Q99714 2/20 0.42
CYP2D6 P10635 1/20 0.42
MEN1 O00255 2/20 0.42
MAPT P10636 2/20 0.42
KMT2A Q03164 2/20 0.42
ACHE P22303 1/20 0.41
ALOX5 P09917 1/20 0.40
TMEM97 Q5BJF2 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4058592 1.00 AMY1A (0.58) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL4064619 0.98 AMY1A (0.55) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL28929859 0.91 AMY1A (0.49) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL8680810 0.89 EGFR (0.49) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL4061628 0.88 SHBG (0.51) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL1904809 0.84 AMY1A (0.58) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL13609019 0.84 AMY1A (0.42) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL8377432 0.83 HSPA5 (0.72) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL278497 0.82 AMY1A (0.45) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL8153644 0.82 AMY1A (0.42) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM AMY1A 2387/4885CYP2C9 1479/4885CYP2C19 1402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.