Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 2/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | CCNC | P24863 | 8/20 | 0.44 |
| ▸ | CDK8 | P49336 | 8/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450621 | 0.76 | PRKCZ (0.60) | TDO2PIK3CDPIK3CBPIK3CGPRKCZ | |
| SCHEMBL4060891 | 0.76 | ESR2 (0.57) | TDO2PIK3CDPIK3CBPIK3CGPRKCZ | |
| SCHEMBL18556708 | 0.75 | CYP11B1 (0.69) | TDO2PIK3CDPIK3CBPIK3CGPRKCZ | |
| SCHEMBL3787569 | 0.75 | MAPK11 (0.47) | PIK3CDPRKCZMAPK14CSNK1DMAPK11 | |
| SCHEMBL15730609 | 0.74 | PIK3CD (0.51) | TDO2PIK3CDPIK3CBPIK3CGPRKCZ | |
| SCHEMBL30165671 | 0.74 | CYP2A6 (0.50) | CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3789748 | 0.74 | CYP2A6 (0.50) | CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL5007325 | 0.73 | PRKCZ (0.70) | TDO2PIK3CDPIK3CBPIK3CGPRKCZ | |
| SCHEMBL30568926 | 0.73 | PIK3CD (0.53) | TDO2PIK3CDPIK3CBPIK3CGPRKCZ | |
| SCHEMBL15723922 | 0.73 | PIK3CD (0.50) | TDO2PIK3CDPIK3CBPIK3CGPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049555-A2 | ORGANIC IRIDIUM COMPOSITIONS AND THEIR USE IN ELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008014037-A2 | ORGANIC IRIDIUM COMPOSITIONS AND THEIR USE IN ELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY (US) | 2008-01-31 | — | — | WO | disclosed |