Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.53 |
| ▸ | TDO2 | P48775 | 2/20 | 0.51 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30568920 | 0.94 | TDO2 (0.51) | PIK3CDPIK3CBPIK3CGTDO2PRKCZ | |
| SCHEMBL15639492 | 0.86 | PIK3CD (0.47) | PIK3CDPIK3CBPIK3CGTDO2PRKCZ | |
| SCHEMBL21415736 | 0.84 | CYP11B2 (0.53) | TDO2PRKCZSLC22A12CYP17A1CYP11B1 | |
| SCHEMBL30568924 | 0.83 | KDM4E (0.41) | TP53IDO1 | |
| SCHEMBL29892464 | 0.82 | CYP1A2 (0.54) | CYP17A1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL5007325 | 0.77 | PRKCZ (0.70) | PIK3CDPIK3CBPIK3CGTDO2PRKCZ | |
| SCHEMBL30568954 | 0.77 | PIK3CA (0.58) | PIK3CDTDO2CYP3A4MAP4K4CLK4 | |
| SCHEMBL30568937 | 0.77 | TDO2 (0.53) | PIK3CDTDO2CYP3A4MAP4K4CLK4 | |
| SCHEMBL4060891 | 0.76 | ESR2 (0.57) | PIK3CDPIK3CBPIK3CGTDO2PRKCZ | |
| SCHEMBL29450621 | 0.76 | PRKCZ (0.60) | PIK3CDPIK3CBPIK3CGTDO2PRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110740991-B | Novel biphenyl compound or salt thereof | 大鹏药品工业株式会社 | 2023-07-04 | — | — | CN | disclosed |