Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | TDO2 | P48775 | 2/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.54 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.51 |
| ▸ | PRKCI | P41743 | 1/20 | 0.48 |
| ▸ | CCNC | P24863 | 5/20 | 0.45 |
| ▸ | CDK8 | P49336 | 5/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450621 | 0.80 | PRKCZ (0.60) | TDO2PIK3CDPIK3CBPIK3CGPRKCZ | |
| SCHEMBL30463004 | 0.80 | ESR2 (0.78) | ESR2HDAC4HDAC2HDAC8ALDH1A1 | |
| SCHEMBL217638 | 0.80 | ESR2 (0.78) | ESR2HDAC4HDAC2HDAC8ALDH1A1 | |
| SCHEMBL18556708 | 0.78 | CYP11B1 (0.69) | ESR2TDO2PIK3CDPIK3CBPIK3CG | |
| SCHEMBL5007325 | 0.77 | PRKCZ (0.70) | ESR2TDO2PIK3CDPIK3CBPIK3CG | |
| SCHEMBL30568926 | 0.76 | PIK3CD (0.53) | TDO2PIK3CDPIK3CBPIK3CGPRKCZ | |
| SCHEMBL4055841 | 0.76 | TDO2 (0.55) | TDO2PIK3CDPIK3CBPIK3CGPRKCZ | |
| SCHEMBL28191731 | 0.75 | PRKCZ (0.68) | ESR2TDO2PRKCZPRKCICDK8 | |
| SCHEMBL18891280 | 0.74 | CYP11B1 (0.69) | ESR2TDO2PRKCZCCNCCDK8 | |
| SCHEMBL27616562 | 0.74 | ESR2 (0.75) | ESR2HDAC4HDAC2HDAC8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049555-A2 | ORGANIC IRIDIUM COMPOSITIONS AND THEIR USE IN ELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008014037-A2 | ORGANIC IRIDIUM COMPOSITIONS AND THEIR USE IN ELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY (US) | 2008-01-31 | — | — | WO | disclosed |