Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 16/20 | 0.44 |
| ▸ | BCHE | P06276 | 15/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.38 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4063234 | 1.00 | ACHE (0.44) | ACHEBCHEFAAHMARK4ASIC3 | |
| SCHEMBL2921664 | 0.80 | HDAC4 (0.42) | BCHEMAPT | |
| SCHEMBL5022783 | 0.79 | ACHE (0.46) | ACHEBCHEFAAHMAPT | |
| SCHEMBL21802665 | 0.77 | MEN1 (0.47) | MEN1KMT2A | |
| SCHEMBL21802668 | 0.77 | MEN1 (0.47) | MEN1KMT2A | |
| SCHEMBL28874730 | 0.77 | TAAR1 (0.42) | — | |
| SCHEMBL17801461 | 0.76 | DAO (0.45) | — | |
| SCHEMBL7855054 | 0.74 | PTGS2 (0.33) | — | |
| SCHEMBL24222513 | 0.74 | ACHE (0.50) | ACHEBCHEFAAHMARK4MEN1 | |
| SCHEMBL19724322 | 0.72 | ACHE (0.49) | ACHEBCHEFAAHMARK4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2109600-A2 | AMORPHOUS AND CRYSTALLINE FORMS OF RIVASTIGMINE HYDROGENTARTRATE | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2009-10-21 | — | — | EP | disclosed |
| WO-2008081041-A2 | AMORPHOUS AND CRYSTALLINE FORMS OF RIVASTIGMINE HYDROGENTARTRATE | KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) | 2008-07-10 | — | — | WO | disclosed |