Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116978 | 0.80 | ALDH1A1 (0.44) | LMNATSHRSCN4ACYP2C19CYP1A2 | |
| SCHEMBL8408220 | 0.80 | HSD17B10 (0.41) | TSHRCYP3A4HSD17B10HPGDCRHBP | |
| SCHEMBL11336983 | 0.77 | SCN4A (0.54) | LMNATSHRHSD17B10HPGDSCN4A | |
| SCHEMBL8408406 | 0.75 | LMNA (0.47) | LMNACYP3A4HSD17B10HPGDCRHBP | |
| SCHEMBL8408182 | 0.75 | SIGMAR1 (0.44) | TSHRSCN4ACYP1A2TDP1L3MBTL1 | |
| SCHEMBL11516388 | 0.74 | LMNA (0.45) | LMNATSHRCYP3A4HSD17B10SCN4A | |
| SCHEMBL8408701 | 0.72 | CYP3A4 (0.41) | CYP3A4HSD17B10HPGDCRHBPCRHR2 | |
| SCHEMBL7628151 | 0.72 | SCN4A (0.33) | CYP3A4HSD17B10HPGDCRHBPCRHR2 | |
| SCHEMBL11239759 | 0.71 | HPGD (0.44) | CYP3A4HSD17B10HPGDCRHBPCRHR2 | |
| SCHEMBL8407186 | 0.71 | HSD17B10 (0.44) | TSHRCYP3A4HSD17B10HPGDCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620093-B1 | PESTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-06-24 | — | — | EP | disclosed |
| EP-1620093-A4 | PESTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-10-31 | — | — | EP | disclosed |
| US-7208450-B2 | Pesticidal (dihalopropenyl) phenylalkyl substituted benzoxazole and benzothiazole derivatives | BAYER CROPSCIENCE AG (DE) | 2007-04-24 | — | — | US | disclosed |
| EP-1620093-A2 | PESTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES | FMC CORPORATION (US) | 2006-02-01 | — | — | EP | disclosed |
| US-20050171356-A1 | Pesticidal (dihalopropenyl) phenylalkyl substituted benzoxazole and benzothiazole derivatives | FMC CORPORATION | 2005-08-04 | — | — | US | disclosed |
| WO-2004099105-A2 | PESTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES | FMC CORPORATION (US) | 2004-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171356-A1 | Pesticidal (dihalopropenyl) phenylalkyl substituted benzoxazole and benzothiazole derivatives | DDT, PDHX, CYP4X1 | LMNA 1944/4885TSHR 1273/4885CYP3A4 591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.