SCHEMBL4056769

SCHEMBL4056769

O=[C]c1ccc([C]=O)c2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 2/20 0.37
IMPDH1 P20839 2/20 0.37
ALDH1A1 P00352 4/20 0.33
HSD17B10 Q99714 3/20 0.33
CYP2A6 P11509 2/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
AR P10275 1/20 0.33
CYP1A2 P05177 3/20 0.32
CYP2C19 P33261 1/20 0.32
IDO1 P14902 1/20 0.32
KDM4E B2RXH2 2/20 0.31
GLA P06280 2/20 0.31
HPGD P15428 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1227243 0.88 CA1 (0.38) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL9035492 0.87 IMPDH2 (0.53) IMPDH2IMPDH1ALDH1A1TSHRCA1
SCHEMBL9670876 0.85 CYP2A6 (0.59) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL8590439 0.85 IDO1 (0.46) ALDH1A1HSD17B10TSHRTDP1IDO1
SCHEMBL3240672 0.85 CYP1A2 (0.59) IMPDH2IMPDH1ALDH1A1HSD17B10CYP2A6
SCHEMBL7207783 0.85 RXFP1 (0.40) IMPDH2IMPDH1ALDH1A1CYP1A2KDM4E
SCHEMBL9097548 0.85 IDO1 (0.59) HSD17B10TSHRTDP1CYP1A2IDO1
SCHEMBL3251429 0.85 ALDH1A1 (0.36) IMPDH2IMPDH1ALDH1A1TSHRKDM4E
SCHEMBL4864417 0.83 PARP1 (0.39) ALDH1A1HSD17B10KDM4EHPGDSMN1; SMN2
SCHEMBL11662454 0.82 GABRA1 (0.35) IMPDH2IMPDH1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3802765-A1 SOIL RELEASE POLYESTERS FOR USE IN DETERGENT COMPOSITIONS Clariant International Ltd (CH) 2021-04-14 EP claimed
WO-2021141807-A1 METHODS FOR PREPARING MIXED POLYAMIDES, POLYIMIDES AND POLYAMIDEIMlDES VIA HYDROTHERMAL POLYMERIZATION EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2021-07-15 WO disclosed
EP-3802765-A1 SOIL RELEASE POLYESTERS FOR USE IN DETERGENT COMPOSITIONS Clariant International Ltd (CH) 2021-04-14 EP disclosed
US-7579127-B2 Blocked polyisocyanates incorporating planar electron-deficient tetracobonylbisimide moieties EASTMAN KODAK COMPANY (US) 2009-08-25 US disclosed
US-20070292795-A1 Blocked polyisocyanates incorporating planar electron-deficient tetracabonylbisimide moieties EASTMAN KODAK COMPANY 2007-12-20 US disclosed
US-5266429-A Binders providing superior discharge and greater electron mobility EASTMAN KODAK COMPANY (US) 1993-11-30 US disclosed
EP-0463830-A2 Melt-stable polyester resin moulding compositions and moulded articles thereof POLYPLASTICS CO. LTD. (JP) 1992-01-02 EP disclosed