SCHEMBL7207783

SCHEMBL7207783

O=[C]c1ccc(Br)c2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 4/20 0.40
PKM P14618 1/20 0.37
PARP1 P09874 1/20 0.35
HTR6 P50406 2/20 0.35
PRNP P04156 1/20 0.35
EPHX1 P07099 2/20 0.34
LMNA P02545 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
FABP4 P15090 1/20 0.33
NPSR1 Q6W5P4 2/20 0.32
GAA P10253 2/20 0.32
MAPK10 P53779 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
CYP1A2 P05177 1/20 0.32
SLC22A12 Q96S37 2/20 0.31
IMPDH2 P12268 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4056769 0.85 IMPDH2 (0.37) LMNAGAAKDM4EALDH1A1MAPT
SCHEMBL14873787 0.77 RXFP1 (0.36) RXFP1PKMPARP1HTR6PRNP
SCHEMBL1343517 0.77 IMPDH2 (0.52) GAAKDM4EALDH1A1MAPTSLC22A12
SCHEMBL198796 0.77 RXFP1 (0.48) RXFP1PKMPARP1HTR6PRNP
SCHEMBL30710586 0.77 RXFP1 (0.48) RXFP1PKMPARP1HTR6PRNP
SCHEMBL29429114 0.77 RXFP1 (0.48) RXFP1PKMPARP1HTR6PRNP
SCHEMBL1227243 0.75 CA1 (0.38) ALDH1A1CYP1A2
SCHEMBL9035492 0.74 IMPDH2 (0.53) GAAKDM4EALDH1A1MAPTSLC22A12
SCHEMBL3251429 0.73 ALDH1A1 (0.36) L3MBTL1FABP4NPSR1GAAKDM4E
SCHEMBL9670876 0.73 CYP2A6 (0.59) RXFP1PKMLMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3743061-A1 CANNABINOIDS AND DERIVATIVES FOR PROMOTING IMMUNOGENICITY OF TUMOR AND INFECTED CELLS Pascal Biosciences Inc. (CA) 2020-12-02 EP claimed
WO-2019144126-A1 CANNABINOIDS AND DERIVATIVES FOR PROMOTING IMMUNOGENICITY OF TUMOR AND INFECTED CELLS PASCAL BIOSCIENCES INC. (CA) 2019-07-25 WO claimed
WO-2020153758-A1 COMPOSITION, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE 엘티소재주식회사 2020-07-30 WO disclosed
EP-2841433-B1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL CO (JP) 2017-06-21 EP disclosed
US-9380782-B2 Tetrazolinone compounds and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-05 US disclosed
WO-2015099508-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 희성소재(주) 2015-07-02 WO disclosed
EP-2841433-A1 TETRAZOLINONE COMPOUNDS AND ITS USE Sumitomo Chemical Company Limited (JP) 2015-03-04 EP disclosed
US-20150031733-A1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-29 US disclosed
WO-2013162077-A1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-10-31 WO disclosed
US-6610848-B1 Platinum 1,2-enedithiolates; L2Pt(S2C2(2-pyridine)(H) wherein L2 is bis(diphenyldiphoshino)methane (dppm), 1,2-bis(diphenyldiphosphino)ethane (dppe) or 1,3-bis(diphenyldiphosphino)propane (dppp) LUMET LLC 2003-08-26 US disclosed
US-5155113-A Administering 5-fluorouracil and derivatives with pyridine and pyridone derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-10-13 US disclosed
EP-0180188-B1 A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-04-15 EP disclosed
EP-0180188-A2 A composition for increasing the anti-cancer activity of an anti-cancer compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-07 EP disclosed
US-4154722-A PHOTOSTABILITY CIBA-GEIGY CORPORATION (US) 1979-05-15 US disclosed
US-4000275-A BENZIMIDAZO(2,1-B) QUINAZOLIN-12(6H)ONES ELI LILLY AND COMPANY (US) 1976-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150031733-A1 TETRAZOLINONE COMPOUNDS AND ITS USE CBR3, CYP51A1, CYP8B1 RXFP1 1392/4885PKM 1989/4885PARP1 4296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.