Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 4/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058099 | 0.88 | RORC (0.47) | GPR119RORC | |
| SCHEMBL3982174 | 0.88 | GPR119 (0.49) | NPY2RGPR119GAACPT2CPT1A | |
| SCHEMBL4053567 | 0.88 | GPR119 (0.47) | GPR119RORC | |
| SCHEMBL4060086 | 0.87 | RORC (0.46) | GPR119RORCCPT2CPT1ACPT1B | |
| SCHEMBL13690470 | 0.87 | GAA (0.43) | NPY2RGPR119GAA | |
| SCHEMBL4387698 | 0.87 | RORC (0.47) | GPR119RORC | |
| SCHEMBL4048482 | 0.86 | GPR119 (0.56) | GPR119RORC | |
| SCHEMBL4057316 | 0.84 | GPR119 (0.58) | GPR119RORC | |
| SCHEMBL4049314 | 0.84 | GPR119 (0.49) | GPR119RORC | |
| SCHEMBL4561845 | 0.84 | GPR119 (0.50) | GPR119RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |