Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4387698 | 0.90 | RORC (0.47) | RORCGPR119ATR | |
| SCHEMBL4053567 | 0.89 | GPR119 (0.47) | RORCGPR119 | |
| SCHEMBL3981756 | 0.88 | GPR119 (0.42) | GPR119MCHR1 | |
| SCHEMBL4056917 | 0.87 | NPY2R (0.48) | RORCGPR119CPT2CPT1ACPT1B | |
| SCHEMBL4048482 | 0.87 | GPR119 (0.56) | RORCGPR119 | |
| SCHEMBL4370580 | 0.86 | ATR (0.34) | RORCGPR119MCHR1ATRGSK3B | |
| SCHEMBL3984054 | 0.86 | GPR119 (0.48) | RORCGPR119PIK3CAMTOR | |
| SCHEMBL4058099 | 0.86 | RORC (0.47) | RORCGPR119 | |
| SCHEMBL4374631 | 0.85 | ITGB3 (0.40) | GPR119MCHR1ATRCCNE2CCNE1 | |
| SCHEMBL4049314 | 0.85 | GPR119 (0.49) | RORCGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |