Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 15/20 | 0.47 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.35 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.35 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2057951 | 0.74 | NPC1 (0.43) | EGLN1FTOEGLN3 | |
| SCHEMBL13908269 | 0.72 | EGLN1 (0.43) | EGLN1EGLN2FTOEGLN3OGFOD1 | |
| SCHEMBL2057284 | 0.70 | KDM4E (0.47) | EGLN1EGLN3L3MBTL1 | |
| SCHEMBL2058021 | 0.67 | EGLN1 (0.39) | EGLN1EGLN3 | |
| SCHEMBL821706 | 0.66 | EGLN1 (0.41) | EGLN1EGLN2FTOEGLN3 | |
| SCHEMBL2057744 | 0.65 | EGLN1 (0.44) | EGLN1 | |
| SCHEMBL3961179 | 0.64 | EGFR (0.49) | EGLN1EGLN3 | |
| SCHEMBL2958240 | 0.63 | EGLN1 (0.49) | EGLN1EGLN2FTOEGLN3APEX1 | |
| SCHEMBL4058857 | 0.63 | EGLN1 (0.57) | EGLN1EGLN3 | |
| SCHEMBL4782873 | 0.62 | EGLN1 (0.63) | EGLN1EGLN2EGLN3OGFOD1HIF1AN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009039323-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-03-26 | — | — | WO | claimed |