Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7918326 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL6918001 | 0.68 | — | — | |
| SCHEMBL29658875 | 0.67 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL5597184 | 0.67 | SIGMAR1 (0.41) | SIGMAR1 | |
| Bromide SCHEMBL6915377 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL6917300 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL4067289 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL27447881 | 0.66 | HTR2A (0.34) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL1980401 | 0.66 | BRD4 (0.35) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6917741 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1710247-B1 | TRANSITION METAL COMPOUND AND CATALYST FOR OLEFIN POLYMERIZATION | IDEMITSU KOSAN CO (JP) | 2009-10-21 | — | — | EP | disclosed |
| EP-1710247-A1 | TRANSITION METAL COMPOUND AND CATALYST FOR OLEFIN POLYMERIZATION | IDEMITSU KOSAN CO., LTD. (JP) | 2006-10-11 | — | — | EP | disclosed |