Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 16/20 | 0.83 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.83 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL682457 | 1.00 | ACE (0.83) | ACEABCB11PDE3ALMNASMN1; SMN2 | |
| SCHEMBL5981613 | 1.00 | ACE (0.83) | ACEABCB11PDE3ALMNASMN1; SMN2 | |
| Maleic Acid SCHEMBL4191053 | 0.96 | ACE (0.77) | ACEABCB11PDE3ALMNASMN1; SMN2 | |
| SCHEMBL682458 | 0.94 | ACE (0.75) | ACEABCB11PDE3ALMNASMN1; SMN2 | |
| SCHEMBL683253 | 0.93 | ACE (0.79) | ACEABCB11PDE3A | |
| SCHEMBL16364866 | 0.93 | ACE (0.86) | ACEABCB11PDE3ALMNASMN1; SMN2 | |
| Quinapril SCHEMBL994608 | 0.91 | ACE (1.00) | ACEABCB11PDE3ALMNASMN1; SMN2 | |
| Quinapril SCHEMBL11294979 | 0.91 | ACE (1.00) | ACEABCB11PDE3ALMNASMN1; SMN2 | |
| Quinapril SCHEMBL9094436 | 0.91 | ACE (1.00) | ACEABCB11PDE3ALMNASMN1; SMN2 | |
| Quinapril SCHEMBL19361887 | 0.91 | ACE (1.00) | ACEABCB11PDE3ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572661-B1 | CRYSTALLINE FORM OF QUINAPRIL HYDROCHLORIDE AND PROCESS FOR PREPARING THE SAME | LUPIN LTD (IN) | 2007-04-25 | — | — | EP | claimed |
| WO-2009113081-A1 | TRIS (HYDROXYMETHYL ) AMINO METHANE SALT OF QUINAPRIL AND RAMIPRIL | LUPIN LIMITED (IN) | 2009-09-17 | — | — | WO | disclosed |
| US-7482361-B2 | Crystalline form for quinapril hydrochloride and process for preparing the same | LUPIN LIMITED (IN) | 2009-01-27 | — | — | US | disclosed |
| EP-1572661-B1 | CRYSTALLINE FORM OF QUINAPRIL HYDROCHLORIDE AND PROCESS FOR PREPARING THE SAME | LUPIN LTD (IN) | 2007-04-25 | — | — | EP | disclosed |
| EP-1611106-B1 | PREPARATION OF QUINAPRIL HYDROCHLORIDE | WARNER LAMBERT CO (US) | 2006-09-20 | — | — | EP | disclosed |
| US-20060058347-A1 | Crystalline form for quinapril hydrochloride and process for preparing the same | LUPIN LIMITED (IN) | 2006-03-16 | — | — | US | disclosed |
| EP-1572661-A1 | CRYSTALLINE FORM OF QUINAPRIL HYDROCHLORIDE AND PROCESS FOR PREPARING THE SAME | Lupin Limited (IN) | 2005-09-14 | — | — | EP | disclosed |
| US-6858735-B2 | Preparation of quinapril hydrochloride | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-22 | — | — | US | disclosed |
| WO-2005010028-A1 | ALPHA-AMINO ACID BENZOTHIAZOLYLTHIO ESTER AS INTERMEDIATES FOR MANUFACTURE OF ACE INHIBITORS AND PROCESS FOR PREPARATION THEREOF | LUPIN LIMITED (IN) | 2005-02-03 | — | — | WO | disclosed |
| WO-2004087671-A1 | PREPARATION OF QUINAPRIL HYDROCHLORIDE | WARNER-LAMBERT COMPANY LLC (US) | 2004-10-14 | — | — | WO | disclosed |
| US-20040192613-A1 | PREPARATION OF QUINAPRIL HYDROCHLORIDE | JENNINGS SANDRA MARIE (US) | 2004-09-30 | — | — | US | disclosed |
| WO-2004054980-A1 | CRYSTALLINE FORM OF QUINAPRIL HYDROCHLORIDE AND PROCESS FOR PREPARING THE SAME | LUPIN LIMITED (IN) | 2004-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058347-A1 | Crystalline form for quinapril hydrochloride and process for preparing the same | ADH1C, NPPA, ADH1A | ACE 14/4885ABCB11 3360/4885PDE3A 43/4885 |
| US-20040192613-A1 | PREPARATION OF QUINAPRIL HYDROCHLORIDE | PEPD, UBE2L6, GABRD | ACE 9/4885ABCB11 1555/4885PDE3A 419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.