Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058075 | 1.00 | PTPN1 (0.45) | PTPN1ALOX5HPGDALDH1A1MAPT | |
| SCHEMBL4050515 | 0.91 | HPGD (0.48) | PTPN1ALOX5HPGDARPOLB | |
| SCHEMBL4050517 | 0.91 | HPGD (0.48) | PTPN1ALOX5HPGDARPOLB | |
| SCHEMBL4054941 | 0.91 | HPGD (0.48) | PTPN1ALOX5HPGDALDH1A1MAPT | |
| SCHEMBL4054943 | 0.91 | HPGD (0.48) | PTPN1ALOX5HPGDALDH1A1MAPT | |
| SCHEMBL4052876 | 0.91 | PTPN1 (0.49) | PTPN1ALOX5HPGDARPOLB | |
| SCHEMBL4052873 | 0.91 | PTPN1 (0.49) | PTPN1ALOX5HPGDARPOLB | |
| SCHEMBL4052918 | 0.90 | ALOX5 (0.52) | PTPN1ALOX5HPGDALDH1A1AR | |
| SCHEMBL4052922 | 0.90 | ALOX5 (0.52) | PTPN1ALOX5HPGDALDH1A1AR | |
| SCHEMBL4054032 | 0.90 | ALOX5 (0.46) | PTPN1ALOX5HPGDARPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |