Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 7/20 | 0.47 |
| ▸ | FEN1 | P39748 | 7/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058096 | 0.85 | ALOX5AP (0.56) | ALOX5APFEN1 | |
| SCHEMBL2803354 | 0.85 | NSD2 (0.58) | NSD2ALDH1A1ALOX5APFEN1KDM4E | |
| SCHEMBL24429391 | 0.85 | NSD2 (0.51) | NSD2ALDH1A1ALOX5APFEN1KDM4E | |
| SCHEMBL3257198 | 0.85 | KAT6A (0.49) | ALDH1A1KAT6AEDNRAGBA1 | |
| SCHEMBL14675795 | 0.80 | KAT6A (0.53) | ALDH1A1KAT6AMEN1KMT2AGBA1 | |
| SCHEMBL24429357 | 0.80 | MAPT (0.50) | NSD2ALDH1A1ALOX5APFEN1KDM4E | |
| SCHEMBL1621373 | 0.79 | ALDH1A1 (0.67) | ALDH1A1KAT6AALOX5APFEN1EDNRA | |
| SCHEMBL24429463 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KAT6AALOX5APFEN1EDNRA | |
| SCHEMBL6308004 | 0.79 | ALOX5AP (0.56) | NSD2ALOX5APFEN1 | |
| SCHEMBL1028459 | 0.79 | KAT6A (0.53) | ALDH1A1KAT6AEDNRAMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220194945-A1 | Imidazolopyridine Compounds For IRE1 Inhibition | Optikira, LLC | 2022-06-23 | — | — | US | disclosed |
| US-20220153734-A1 | Pyrazolopyridine Compounds For IRE1 Inhibition | Optikira, LLC | 2022-05-19 | — | — | US | disclosed |
| CN-107001309-B | Bis (sulfonamide) derivatives and their use as MPGES inhibitors | 格辛塔制药公司 | 2021-03-05 | — | — | CN | disclosed |
| EP-3224253-B1 | BIS (SULFONAMIDE) DERIVATIVES AND THEIR USE AS MPGES INHIBITORS | GESYNTA PHARMA AB (SE) | 2019-10-30 | — | — | EP | disclosed |
| US-10227296-B2 | Bis(sulfonamide) derivatives and their use as mPGES inhibitors | Arcturum Real Estate AB (SE) | 2019-03-12 | — | — | US | disclosed |
| US-10227296-B2 | Bis(sulfonamide) derivatives and their use as mPGES inhibitors | Arcturum Real Estate AB (SE) | 2019-03-12 | — | — | US | disclosed |
| US-10081614-B2 | Bis(sulfonamide) derivatives and their use as mPGES inhibitors | ACTURUM REAL ESTATE AB (SE) | 2018-09-25 | — | — | US | disclosed |
| US-9938301-B2 | Dihydropyrimido fused ring derivative as HBV inhibitor | QILU PHARMACEUTICAL CO., LTD. (CN) | 2018-04-10 | — | — | US | disclosed |
| US-9938301-B2 | Dihydropyrimido fused ring derivative as HBV inhibitor | QILU PHARMACEUTICAL CO., LTD. (CN) | 2018-04-10 | — | — | US | disclosed |
| US-20180002278-A1 | BIS(SULFONAMIDE) DERIVATIVES AND THEIR USE AS MPGES INHIBITORS | ACTURUM REAL ESTATE AB (SE) | 2018-01-04 | — | — | US | disclosed |
| EP-2278881-A1 | HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PHENYLSULFONYLUREAS | Bayer CropScience AG (DE) | 2011-02-02 | — | — | EP | disclosed |
| US-7855166-B2 | Sulfonylamino(thio)carbonyl compounds | BAYER CROPSCIENCE GMBH (DE) | 2010-12-21 | — | — | US | disclosed |
| US-20100317524-A1 | Sulfonylureas | BAYER CROPSCIENCE AG (DE) | 2010-12-16 | — | — | US | disclosed |
| WO-2009127378-A1 | HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PHENYLSULFONYLUREAS | BAYER CROPSCIENCE AG (DE) | 2009-10-22 | — | — | WO | disclosed |
| WO-2009127378-A1 | HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PHENYLSULFONYLUREAS | BAYER CROPSCIENCE AG (DE) | 2009-10-22 | — | — | WO | disclosed |
| EP-2110019-A1 | Herbicidal compounds based on N-Azinyl-N'-phenylsulfonylureas | Bayer CropScience AG (DE) | 2009-10-21 | — | — | EP | disclosed |
| US-20060264329-A1 | Sulfonylureas | BAYER CROPSCIENCE GMBH (DE) | 2006-11-23 | — | — | US | disclosed |
| US-20060258536-A1 | Sulfonylamino(thio)carbonyl compounds | BAYER CROPSCIENCE GMBH (DE) | 2006-11-16 | — | — | US | disclosed |
| EP-1717228-A1 | Sulfonylamino(thio)carbonylderivatives as herbicides or plant growth regulators | Bayer CropScience GmbH (DE) | 2006-11-02 | — | — | EP | disclosed |
| EP-1717232-A1 | Phenylsulfonylureas with herbicidal activity | Bayer CropScience GmbH (DE) | 2006-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317524-A1 | Sulfonylureas | IAPP, SLC5A2, SLC5A1 | NSD2 3546/4885ALDH1A1 1343/4885KAT6A 4719/4885 |
| US-10227296-B2 | Bis(sulfonamide) derivatives and their use as mPGES inhibitors | PTGES, PTGS1, PTGES2 | NSD2 908/4885ALDH1A1 394/4885KAT6A 4077/4885 |
| US-20220194945-A1 | Imidazolopyridine Compounds For IRE1 Inhibition | XBP1, ERN2, ERN1 | NSD2 3602/4885ALDH1A1 2541/4885KAT6A 4765/4885 |
| US-20060258536-A1 | Sulfonylamino(thio)carbonyl compounds | TST, CBR3, MYB | NSD2 2595/4885ALDH1A1 1134/4885KAT6A 2862/4885 |
| US-20220153734-A1 | Pyrazolopyridine Compounds For IRE1 Inhibition | XBP1, ERN1, ERN2 | NSD2 3784/4885ALDH1A1 2438/4885KAT6A 4658/4885 |
| US-10081614-B2 | Bis(sulfonamide) derivatives and their use as mPGES inhibitors | PTGES, PTGS1, PTGES2 | NSD2 908/4885ALDH1A1 394/4885KAT6A 4077/4885 |
| US-20060264329-A1 | Sulfonylureas | INSR, FFAR3, GPR119 | NSD2 1548/4885ALDH1A1 1744/4885KAT6A 2091/4885 |
| US-20180002278-A1 | BIS(SULFONAMIDE) DERIVATIVES AND THEIR USE AS MPGES INHIBITORS | PTGES, PTGS1, PTGES2 | NSD2 908/4885ALDH1A1 394/4885KAT6A 4077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.