Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 10/20 | 0.54 |
| ▸ | ALOX5AP | P20292 | 10/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1621373 | 0.84 | ALDH1A1 (0.67) | FEN1ALOX5APALDH1A1CYP1A2 | |
| SCHEMBL4058096 | 0.82 | ALOX5AP (0.56) | FEN1ALOX5AP | |
| SCHEMBL15366568 | 0.79 | FEN1 (0.54) | FEN1ALOX5APALDH1A1 | |
| SCHEMBL5831677 | 0.79 | ALOX5AP (0.48) | FEN1ALOX5APALDH1A1GRIA4 | |
| SCHEMBL14956305 | 0.78 | GAA (0.43) | FEN1ALOX5AP | |
| SCHEMBL4731653 | 0.77 | CYP1A2 (0.55) | FEN1ALOX5APALDH1A1CYP1A2 | |
| SCHEMBL1846856 | 0.77 | CASP1 (0.51) | FEN1ALOX5APCYP1A2 | |
| SCHEMBL791010 | 0.77 | PTGES2 (0.54) | FEN1ALOX5APALDH1A1CYP1A2 | |
| SCHEMBL29689413 | 0.76 | SLC40A1 (0.51) | FEN1ALOX5APALDH1A1CYP1A2 | |
| SCHEMBL15924903 | 0.75 | FEN1 (0.58) | FEN1ALOX5APGRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2951170-A2 | FLAP MODULATORS | Janssen Pharmaceutica, N.V. (BE) | 2015-12-09 | — | — | EP | claimed |
| WO-2014121055-A2 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-08-07 | — | — | WO | claimed |