Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 16/20 | 0.47 |
| ▸ | FEN1 | P39748 | 16/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PARG | Q86W56 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878904 | 0.84 | ALOX5AP (0.45) | ALOX5APFEN1 | |
| SCHEMBL24429357 | 0.84 | MAPT (0.50) | ALOX5APFEN1MAPTNPSR1PARG | |
| SCHEMBL15924550 | 0.83 | PKM (0.43) | ALOX5APFEN1LMNASMN1; SMN2 | |
| SCHEMBL7404601 | 0.82 | NSD2 (0.51) | ALOX5APFEN1MAPTNPSR1PARG | |
| SCHEMBL10730171 | 0.82 | PARG (0.43) | ALOX5APFEN1MAPTNPSR1PARG | |
| SCHEMBL10571163 | 0.79 | PARG (0.41) | ALOX5APFEN1MAPTNPSR1PARG | |
| SCHEMBL7554444 | 0.78 | ALOX5AP (0.48) | ALOX5APFEN1MAPTNPSR1PARG | |
| SCHEMBL1968159 | 0.77 | ALOX5AP (0.59) | ALOX5APFEN1PARG | |
| SCHEMBL7411585 | 0.77 | PTGS2 (0.52) | HPGD | |
| SCHEMBL3767355 | 0.76 | MAPT (0.44) | ALOX5APFEN1MAPTNPSR1PARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824826-A4 | ARYL SULFONIC PYRIDOXINES AS ANTIPLATELET AGENTS | MEDICURE INT INC (BB) | 2009-06-03 | — | — | EP | disclosed |
| EP-1824826-A1 | ARYL SULFONIC PYRIDOXINES AS ANTIPLATELET AGENTS | Medicure International Inc. (BB) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006045204-A1 | ARYL SULFONIC PYRIDOXINES AS ANTIPLATELET AGENTS | MEDICURE INTERNATIONAL INC. (CA) | 2006-05-04 | — | — | WO | disclosed |
| EP-0946508-A1 | NITROGEN CONTAINING HETEROAROMATICS AS FACTOR Xa INHIBITORS | Du Pont Pharmaceuticals Company (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028269-A1 | NITROGEN CONTAINING HETEROAROMATICS AS FACTOR Xa INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |