Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 4/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.40 |
| ▸ | FEN1 | P39748 | 4/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12932761 | 0.84 | LMNA (0.50) | PARGMAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL7404601 | 0.82 | NSD2 (0.51) | PARGMAPTNPSR1LMNASMN1; SMN2 | |
| SCHEMBL4058098 | 0.82 | ALOX5AP (0.47) | PARGMAPTNPSR1LMNASMN1; SMN2 | |
| SCHEMBL7406577 | 0.79 | PARG (0.41) | PARGMAPTNPSR1LMNASMN1; SMN2 | |
| SCHEMBL10571163 | 0.79 | PARG (0.41) | PARGMAPTNPSR1LMNASMN1; SMN2 | |
| SCHEMBL15916202 | 0.78 | SLC40A1 (0.48) | PARGMAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL1968159 | 0.77 | ALOX5AP (0.59) | PARGALOX5APFEN1EDNRBEDNRA | |
| SCHEMBL8997319 | 0.77 | KAT6A (0.47) | CYP2A6MAPTNPSR1LMNASMN1; SMN2 | |
| SCHEMBL28820849 | 0.77 | PARG (0.55) | PARGCYP2A6MAPTLMNASMN1; SMN2 | |
| SCHEMBL7406190 | 0.75 | PARG (0.38) | PARGMAPTNPSR1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4643761-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-02-17 | — | — | US | disclosed |