Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 18/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075882 | 0.78 | EGLN1 (0.48) | EGLN1BBOX1ASPHKDM8 | |
| SCHEMBL4059048 | 0.71 | EGLN1 (0.41) | EGLN1BBOX1ASPHKDM8 | |
| SCHEMBL13908269 | 0.68 | EGLN1 (0.43) | EGLN1AKR1B1 | |
| SCHEMBL4059804 | 0.65 | EGLN3 (0.40) | EGLN1BBOX1ASPHKDM8 | |
| SCHEMBL4065499 | 0.64 | RPA1 (0.58) | EGLN1BBOX1ASPHKDM8 | |
| SCHEMBL5308223 | 0.64 | MEN1 (0.52) | EGLN1 | |
| SCHEMBL3421207 | 0.64 | SLC22A12 (0.54) | — | |
| SCHEMBL12777777 | 0.62 | EGLN1 (0.48) | EGLN1AKR1B1 | |
| SCHEMBL3422554 | 0.62 | EGLN1 (0.66) | EGLN1BBOX1ASPHKDM8 | |
| SCHEMBL12101567 | 0.61 | EGLN1 (0.54) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009039323-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-03-26 | — | — | WO | claimed |
| WO-2009039323-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-03-26 | — | — | WO | disclosed |
| WO-2009039323-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-03-26 | — | — | WO | disclosed |