SCHEMBL4058409

SCHEMBL4058409

Cc1cc(Cc2cc(Cl)c(O)cc2O)c(O)c(Cc2cc(Cl)c(O)cc2O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.59
HIF1A Q16665 5/20 0.49
CYP2C9 P11712 5/20 0.49
CYP2C19 P33261 5/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
HSPA5 P11021 2/20 0.46
HSD17B10 Q99714 4/20 0.40
CYP2D6 P10635 2/20 0.40
HSP90AA1 P07900 5/20 0.38
HPGD P15428 3/20 0.38
MAPT P10636 3/20 0.38
CYP3A4 P08684 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
SLC22A1 O15245 1/20 0.38
USP2 O75604 1/20 0.38
LMNA P02545 1/20 0.38
HSPD1 P10809 1/20 0.38
IDO1 P14902 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27420293 0.84 AMY1A (0.68) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL27420295 0.84 AMY1A (0.68) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL1994665 0.81 AMY1A (0.63) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL30320307 0.81 AMY1A (0.63) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL8077742 0.79 AMY1A (0.61) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL23720968 0.79 AMY1A (0.43) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL69852 0.78 HSPA5 (0.53) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL14461926 0.77 CYP2C9 (0.55) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL23339864 0.76 AMY1A (0.67) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL13609011 0.75 CYP2C9 (0.66) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210284788-A1 THERMALLY CONDUCTIVE MATERIAL-FORMING COMPOSITION, THERMALLY CONDUCTIVE MATERIAL, THERMALLY CONDUCTIVE SHEET, DEVICE WITH THERMALLY CONDUCTIVE LAYER, AND FILM FUJIFILM CORPORATION (JP) 2021-09-16 US disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed
EP-0685766-B1 Selected trinuclear novolak oligomers OLIN MICROELECTRONIC CHEM INC (US) 2001-09-26 EP disclosed
EP-0740213-B1 Positive photoresist composition FUJI PHOTO FILM CO LTD (JP) 2001-08-08 EP disclosed
EP-0477691-B2 Positive-type photoresist composition FUJI PHOTO FILM CO LTD (JP) 2001-03-07 EP disclosed
EP-0886183-A1 Positive-working photoresist composition Fuji Photo Film Co., Ltd. (JP) 1998-12-23 EP disclosed
EP-0744661-B1 Positive photoresist composition FUJI PHOTO FILM CO LTD (JP) 1998-10-07 EP disclosed
US-5750310-A BLEND OF ALKALI SOLUBLE RESIN, 1,2-NAPHTHOQUINONEDIAZIDE SULFONIC ACID AND TETRAHYDROXY COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1998-05-12 US disclosed
EP-0451170-B1 SELECTED TRINUCLEAR NOVOLAK OLIGOMER DERIVATIVES AS PHOTOACTIVE COMPOUNDS AND THEIR USE IN RADIATION SENSITIVE MIXTURES OCG MICROELECTRONIC MATERIALS (US) 1996-04-24 EP disclosed
EP-0685766-A1 Selected trinuclear novolak oligomers and their use in photo-active compounds and radiation sensitive mixtures OCG MICROELECTRONIC MATERIALS, INC. (US) 1995-12-06 EP disclosed
EP-0658807-A1 Positive-working photoresist composition FUJI PHOTO FILM CO., LTD. (JP) 1995-06-21 EP disclosed
US-5340686-A Alkali soluble phenol novolak resin, 1,2-quinone diazide compound and low molecular weight novolak compound FUJI PHOTO FILM CO., LTD. (JP) 1994-08-23 US disclosed
EP-0477691-A2 Positive-type photoresist composition FUJI PHOTO FILM CO., LTD. (JP) 1992-04-01 EP disclosed
EP-0445680-A2 Positive type photoresist composition FUJI PHOTO FILM CO., LTD. (JP) 1991-09-11 EP disclosed
US-4992356-A Positive photoresists OLIN HUNT SPECIALTY PRODUCTS INC. (US) 1991-02-12 US disclosed
US-4992596-A Selected trinuclear novolak oligomers and their use in photoactive compounds and radiation sensitive mixtures OLIN HUNT SPECIALTY PRODUCTS INC. (US) 1991-02-12 US disclosed
US-4957846-A PHOTORESISTS, PHOTOLITHOGRAPHY, PRINTED CIRCUITS OLIN HUNT SPECIALTY PRODUCTS INC. (US) 1990-09-18 US disclosed
WO-1990007538-A1 SELECTED TRINUCLEAR NOVOLAK OLIGOMERS AND THEIR USE IN PHOTOACTIVE COMPOUNDS AND RADIATION SENSITIVE MIXTURES OLIN HUNT SPECIALTY PRODUCTS INC. (US) 1990-07-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM AMY1A 2387/4885HIF1A 72/4885CYP2C9 1479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.