SCHEMBL69852

SCHEMBL69852

Cc1cc(Cl)c(O)c(Cc2cc(C)cc(Cl)c2O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 3/20 0.53
AMY1A P0DUB6 1/20 0.53
CYP2C19 P33261 6/20 0.52
HIF1A Q16665 6/20 0.52
CYP2C9 P11712 5/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
HSP90AA1 P07900 3/20 0.48
HSD17B10 Q99714 6/20 0.46
CYP2D6 P10635 2/20 0.46
CYP3A4 P08684 4/20 0.42
CYP1A2 P05177 2/20 0.42
SIRT1 Q96EB6 1/20 0.41
HPGD P15428 4/20 0.40
TSHR P16473 3/20 0.40
NPC1 O15118 2/20 0.40
RECQL P46063 2/20 0.40
THRB P10828 2/20 0.40
MAPK1 P28482 2/20 0.40
MEN1 O00255 2/20 0.40
USP2 O75604 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4444016 0.84 SHBG (0.44) HSPA5AMY1ACYP2C19HIF1ACYP2C9
SCHEMBL16077899 0.83 NPC1 (0.38) HSPA5AMY1ACYP2C19HIF1ACYP2C9
SCHEMBL14534585 0.83 THRB (0.38) HSPA5AMY1ACYP2C19HIF1ACYP2C9
SCHEMBL14430758 0.83 NPC1 (0.38) HSPA5AMY1ACYP2C19HIF1ACYP2C9
SCHEMBL27679370 0.81 ALOX5 (0.40) HSPA5AMY1ACYP2C19HIF1ACYP2C9
SCHEMBL64932 0.80 ALDH1A1 (0.58) CYP2C19HIF1ACYP2C9SMN1; SMN2HSD17B10
SCHEMBL15758050 0.78 GAA (0.43) HSPA5AMY1AHPGDNPC1MEN1
SCHEMBL4058409 0.78 AMY1A (0.59) HSPA5AMY1ACYP2C19HIF1ACYP2C9
SCHEMBL8822890 0.77 HSP90AA1 (0.48) HSPA5CYP2C19HIF1ACYP2C9SMN1; SMN2
SCHEMBL359097 0.77 HIF1A (0.41) HSPA5AMY1ACYP2C19HIF1ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 HSPA5 133/4885AMY1A 2199/4885CYP2C19 3009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.