SCHEMBL4059093

SCHEMBL4059093

O=C(O)OOC(=O)CNc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
MAPT P10636 3/20 0.44
KMT2A Q03164 3/20 0.44
RAB9A P51151 2/20 0.44
LMNA P02545 2/20 0.44
MEN1 O00255 2/20 0.44
ERCC1 P07992 3/20 0.42
ERCC4 Q92889 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 1/20 0.42
HPGD P15428 1/20 0.42
AGTR1 P30556 1/20 0.42
GAA P10253 2/20 0.41
PKM P14618 1/20 0.41
KDM4E B2RXH2 1/20 0.41
AKR1C3 P42330 1/20 0.41
PTPN7 P35236 1/20 0.40
PTPN12 Q05209 1/20 0.40
TP53 P04637 1/20 0.39
EPHX1 P07099 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26135537 0.94 ALDH1A1 (0.47) ALDH1A1MAPTKMT2ARAB9ALMNA
SCHEMBL2238017 0.82 ALDH1A1 (0.46) ALDH1A1MAPTKMT2ARAB9ALMNA
SCHEMBL20594029 0.82 ALDH1A1 (0.47) ALDH1A1MAPTKMT2ARAB9ALMNA
SCHEMBL658053 0.80 LMNA (0.54) ALDH1A1MAPTKMT2ARAB9ALMNA
SCHEMBL8840792 0.80 ALDH1A1 (0.46) ALDH1A1MAPTKMT2ARAB9ALMNA
Hydrochloric Acid SCHEMBL76327 0.78 LMNA (0.53) ALDH1A1MAPTKMT2ARAB9ALMNA
Benzene SCHEMBL28330086 0.78 LMNA (0.53) ALDH1A1MAPTKMT2ARAB9ALMNA
SCHEMBL11416059 0.78 ALDH1A1 (0.45) ALDH1A1MAPTKMT2ARAB9ALMNA
SCHEMBL17527568 0.78 ALDH1A1 (0.45) ALDH1A1MAPTKMT2ARAB9ALMNA
SCHEMBL28554321 0.78 ALDH1A1 (0.45) ALDH1A1MAPTKMT2ARAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6727076-B2 UTILIZES A GEL FORMING MATRIX FOR THE RAPID SCREENING OF CLINICAL AND ENVIRONMENTAL CULTURES BIOLOG, INC. 2004-04-27 US claimed
US-6472201-B1 GROWING AND TESTING MICROORGANISMS IN A MULTITEST FORMAT WHICH UTILIZES A GEL FORMING MATRIX FOR THE RAPID SCREENING OF CLINICAL AND ENVIRONMENTAL CULTURES BIOLOG, INC. 2002-10-29 US claimed
US-9274101-B2 Methods and kits for obtaining a metabolic profile of living animal cells BIOLOG, INC. (US) 2016-03-01 US disclosed
EP-1501938-B1 ANALYSIS OF SUBSTRATE UTILIZATION BY ANIMAL OR PLANT CELLS BIOLOG INC (US) 2009-10-21 EP disclosed
EP-1501938-A4 COMPARATIVE PHENOTYPE ANALYSIS OF CELLS, INCLUDING TESTING OF BIOLOGICALLY ACTIVE COMPOUNDS BIOLOG INC (US) 2007-01-03 EP disclosed
US-20060286627-A1 Methods and kits for obtaining a metabolic profile of living animal cells BIOLOG INC. (US) 2006-12-21 US disclosed
US-20050260558-A1 Comparative phenotype analysis of cells including testing of biologically active chemicals BIOLOG INC. (US) 2005-11-24 US disclosed
EP-1501938-A2 COMPARATIVE PHENOTYPE ANALYSIS OF CELLS, INCLUDING TESTING OF BIOLOGICALLY ACTIVE COMPOUNDS BIOLOG, INC. (US) 2005-02-02 EP disclosed
EP-1088097-A4 COMPARATIVE PHENOTYPE ANALYSIS BIOLOG INC (US) 2004-12-01 EP disclosed
US-6727076-B2 UTILIZES A GEL FORMING MATRIX FOR THE RAPID SCREENING OF CLINICAL AND ENVIRONMENTAL CULTURES BIOLOG, INC. 2004-04-27 US disclosed
US-6686173-B2 MONITORING CELL PREPARATIONS FOR PREFERENTIAL RESPONSE SUBSTRATES; OBTAIN MICROTITER PLATES, FILL WITH CELLS, INCUBATE WITH SUBSTRATE, MONITOR RESPONSE TO SUBSTRATE BIOLOG, INC. 2004-02-03 US disclosed
US-20020164574-A1 Methods for utilization of microplates in chemical classification and analysis PARADIGM GENETICS, INC. 2002-11-07 US disclosed
US-6472201-B1 GROWING AND TESTING MICROORGANISMS IN A MULTITEST FORMAT WHICH UTILIZES A GEL FORMING MATRIX FOR THE RAPID SCREENING OF CLINICAL AND ENVIRONMENTAL CULTURES BIOLOG, INC. 2002-10-29 US disclosed
US-20020110848-A1 Comparative phenotype analysis BIOLOG, INC. 2002-08-15 US disclosed
US-6387651-B1 PREPARING SUSPENSIONS OF EACH CELL PREPARATION, PLACING SUSPENSIONS INTO TESTING DEVICE, DETECTING RESPONSE OF CELL PREPARATIONS TO AT LEAST ONE TEST SUBSTRATE, AND COMPARING RESPONSES BIOLOG, INC. 2002-05-14 US disclosed
EP-1088097-A1 COMPARATIVE PHENOTYPE ANALYSIS BIOLOG, INC. (US) 2001-04-04 EP disclosed
EP-0816327-B1 Process for preparing N-(2-carboxy-5-chloro-phenyl)glycine CLARIANT GMBH (DE) 2001-01-17 EP disclosed
US-6046021-A Comparative phenotype analysis of two or more microorganisms using a plurality of substrates within a multiwell testing device BIOLOG, INC. (US) 2000-04-04 US disclosed
WO-1999066066-A1 COMPARATIVE PHENOTYPE ANALYSIS BIOLOG, INC. (US) 1999-12-23 WO disclosed
EP-0816327-A1 Process for preparing N-(2-carboxy-5-chloro-phenyl)glycine Clariant GmbH (DE) 1998-01-07 EP disclosed