Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4226154 | 0.87 | CYSLTR2 (0.38) | TBXAS1TBXA2R | |
| SCHEMBL4052445 | 0.83 | LTB4R (0.32) | — | |
| SCHEMBL4231281 | 0.82 | CYSLTR1 (0.36) | TBXAS1TBXA2R | |
| SCHEMBL4231288 | 0.82 | CYSLTR1 (0.36) | TBXAS1TBXA2R | |
| SCHEMBL4054249 | 0.76 | CYSLTR2 (0.38) | TBXAS1TBXA2R | |
| SCHEMBL4230528 | 0.75 | CYSLTR2 (0.37) | TBXAS1TBXA2R | |
| SCHEMBL4060896 | 0.73 | CALCA (0.33) | — | |
| SCHEMBL7808169 | 0.73 | FFAR1 (0.36) | TBXA2RFFAR4 | |
| SCHEMBL4748814 | 0.72 | LTB4R (0.38) | TBXAS1 | |
| SCHEMBL4052827 | 0.72 | CYSLTR1 (0.39) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | disclosed |
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | disclosed |
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | disclosed |
| EP-1560834-B1 | NEW TRICYCLIC DERIVATIVES AS LTD4 ANTAGONISTS | ALMIRALL LAB (ES) | 2008-06-25 | — | — | EP | disclosed |