Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050972 | 0.84 | LTB4R (0.45) | LTB4R | |
| SCHEMBL4059330 | 0.83 | TBXAS1 (0.36) | — | |
| SCHEMBL4060896 | 0.79 | CALCA (0.33) | — | |
| SCHEMBL4052135 | 0.78 | GLA (0.39) | — | |
| SCHEMBL4052130 | 0.78 | GLA (0.39) | — | |
| SCHEMBL4052805 | 0.72 | LTB4R (0.46) | LTB4R | |
| SCHEMBL4054801 | 0.69 | P2RX7 (0.34) | — | |
| SCHEMBL4748814 | 0.69 | LTB4R (0.38) | LTB4R | |
| SCHEMBL4226154 | 0.69 | CYSLTR2 (0.38) | LTB4R | |
| SCHEMBL7810780 | 0.67 | LTB4R (0.39) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | disclosed |
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | disclosed |
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | disclosed |
| EP-1560834-B1 | NEW TRICYCLIC DERIVATIVES AS LTD4 ANTAGONISTS | ALMIRALL LAB (ES) | 2008-06-25 | — | — | EP | disclosed |