Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059918 | 1.00 | ADORA3 (0.35) | ADORA3HPSEDHFRKDM4ENPC1 | |
| SCHEMBL4061527 | 0.82 | ALDH1A3 (0.45) | ADORA3KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4061530 | 0.82 | ALDH1A3 (0.45) | ADORA3KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4066331 | 0.81 | PSEN1 (0.32) | ADORA3KDM4EPSEN1PSEN2APH1B | |
| SCHEMBL4066336 | 0.81 | PSEN1 (0.32) | ADORA3KDM4EPSEN1PSEN2APH1B | |
| SCHEMBL4062013 | 0.80 | HTR4 (0.37) | ADORA3 | |
| SCHEMBL4062015 | 0.80 | HTR4 (0.37) | ADORA3 | |
| SCHEMBL4063309 | 0.78 | KDM4E (0.34) | HPSEDHFRKDM4ENPC1RAB9A | |
| SCHEMBL4063303 | 0.78 | KDM4E (0.34) | HPSEDHFRKDM4ENPC1RAB9A | |
| SCHEMBL4066428 | 0.74 | SSTR4 (0.36) | ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041153-B1 | NEW 5-THIOXYLOPYRANOSE DERIVATIVES | FOURNIER LAB SA (FR) | 2009-10-21 | — | — | EP | disclosed |