Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.50 |
| ▸ | KIF23 | Q02241 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3863849 | 0.82 | KIF11 (0.49) | KIF11KIF23KDM4EGAAMAPT | |
| SCHEMBL4057634 | 0.82 | KIF11 (0.51) | KIF11KIF23KDM4EGAAMAPT | |
| SCHEMBL3866928 | 0.76 | KIF11 (0.52) | KIF11KIF23 | |
| SCHEMBL3871323 | 0.76 | KIF11 (0.49) | KIF11KIF23KDM4EGAAMAPT | |
| SCHEMBL4039832 | 0.75 | KIF11 (0.48) | KIF11KIF23KDM4EGAAMAPT | |
| SCHEMBL5316065 | 0.75 | KIF11 (0.56) | KIF11KIF23KDM4EGAAMAPT | |
| SCHEMBL4044893 | 0.74 | KIF11 (0.42) | KIF11KIF23GAAALDH1A1 | |
| SCHEMBL4061532 | 0.74 | KIF11 (0.41) | KIF11KIF23MAPTALDH1A1 | |
| SCHEMBL5899029 | 0.73 | KIF11 (0.47) | KIF11KIF23KDM4EGAAMAPT | |
| SCHEMBL4063001 | 0.73 | KIF11 (0.72) | KIF11KIF23 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781673-B1 | SELECTED FUSED HETEROCYCLICS AND USES THEREOF | ASTRAZENECA AB (SE) | 2009-10-21 | — | — | EP | disclosed |